SynthesisBMC pregnancy and childbirth2018
A systematic review of cardiac time intervals utilising non-invasive fetal electrocardiogram in normal fetuses.
Synthesis in BMC pregnancy and childbirth, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- A systematic review on the utility of non-invasive electrophysiological assessment in evaluating for intra uterine growth restriction.BMC pregnancy and childbirth · 2019Pooled it
- Assessing signal loss, accuracy, and acceptability of an ambulatory fetal electrocardiography with cardiotocography in the antepartum and intrapartum phases.Acta obstetricia et gynecologica Scandinavica · 2026Article
- Physiological Determinants of PR Interval in Healthy Fetuses: Insights from Correlation and Regression Modeling.Journal of clinical medicine · 2025Article
- Multichannel high noise level ECG denoising based on adversarial deep learning.Scientific reports · 2024Article
- Fetal electrocardiography and artificial intelligence for prenatal detection of congenital heart disease.Acta obstetricia et gynecologica Scandinavica · 2023Article
- Effectiveness of ambulatory non-invasive fetal electrocardiography: impact of maternal and fetal characteristics.Acta obstetricia et gynecologica Scandinavica · 2023Observational
- Ambulatory antenatal fetal electrocardiography in high-risk pregnancies (AMBER): protocol for a pilot prospective cohort study.BMJ open · 2023Article
- Use of proposed systolic and myocardial performance indices derived from simultaneous ECG and PCG recordings to assess cardiac function in healthy Beagles.Veterinary world · 2022Article
- Sodium dichloroacetate stimulates cardiac mitochondrial metabolism and improves cardiac conduction in the ovine fetus during labor.American journal of physiology. Regulatory, integrative and comparative physiology · 2022Article
- Harnessing technology to enable all women mobility in labour and birth: feasibility of implementing beltless non-invasive fetal ECG applying the NASSS framework.Pilot and feasibility studies · 2021Article
- A non-invasive multimodal foetal ECG-Doppler dataset for antenatal cardiology research.Scientific data · 2021Article
- Novel Approach to Assess Cardiac Function Using Systolic Performance and Myocardial Performance Indices From Simultaneous Electrocardiography and Phonocardiography Recordings in Dogs With Various Stages of Myxomatous Mitral Valve Disease.Frontiers in veterinary science · 2021Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNon-invasive fetal electrocardiogram (NIFECG) is an evolving technology in fetal surveillance which is attracting increasing research interest. There is however, only limited data outlining the reference ranges for normal cardiac time intervals (CTIs). The objective of our group was to carry out a systematic review to outline normal fetal CTIs using NIFECG.
methodsA systematic review of peer reviewed literature was performed, searching PUBMED,Ovid MEDLINE and EMBASE. The outcomes of interest included fetal CTIs (P wave duration, PR interval, QRS duration and QT interval) and a descriptive summary of relevant studies as well. The outcomes were grouped as early pre-term (≤ 32 weeks), moderate to late pre-term (32-37 weeks) and term (37-41 weeks).
results8 studies were identified as suitable for inclusion. Reference ranges of CTIs were generated. Both PR interval and QRS duration demonstrated a linear correlation with advancing gestation. Several studies also demonstrated a reduction in signal acquisition between 27 and 32 weeks due to the attenuation by vernix caseosa. In this group, both the P wave and T waves were difficult to detect due to signal strength and interference.
conclusionNIFECG demonstrates utility to quantify CTIs in the fetus, particularly at advanced gestations. Larger prospective studies should be directed towards establishing reliable CTIs across various gestations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.