Evidence map›Paper›PMID 30208664›Full record

ReviewMolecules (Basel, Switzerland)2018

Phenolic Compounds in Honey and Their Associated Health Benefits: A Review.

Danila Cianciosi, Tamara Yuliett Forbes-Hernández, Sadia Afrin, Massimiliano Gasparrini, Patricia Reboredo-Rodriguez, Piera Pia Manna, Jiaojiao Zhang, Leire Bravo Lamas, Susana Martínez Flórez, Pablo Agudo Toyos and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Molecules (Basel, Switzerland), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 214 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
214citing papers in PubMed, 3 pooled it
50.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

214 citing papers in PubMed, 3 syntheses or guidelines pooled it, 685 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Tualang Honey: A Decade of Neurological Research.Molecules (Basel, Switzerland) · 2021
    Pooled it
  4. Trial
  5. Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Baseline salivary IL-6 as a predictive biomarker for complementary therapy response in radiation-induced oral mucositis.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Article
  11. Article
  12. Fortified Chestnut Honey Triggers Apoptosis in Colon Cancer Cells.Plant foods for human nutrition (Dordrecht, Netherlands) · 2026
    Article
  13. Article
  14. Review
  15. Article
  16. Review
  17. Article
  18. Article
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154 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 2 countries.

Danila CianciosiDipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche (DISCO)-Sez. Biochimica, Facoltà di Medicina, Università Politecnica delle Marche, 60131 Ancona, Italy. danila.cianciosi@gmail.com.
Tamara Yuliett Forbes-HernándezDipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche (DISCO)-Sez. Biochimica, Facoltà di Medicina, Università Politecnica delle Marche, 60131 Ancona, Italy. tamara.forbe@gmail.com.ORCID 0000-0001-7021-9276
Sadia AfrinDipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche (DISCO)-Sez. Biochimica, Facoltà di Medicina, Università Politecnica delle Marche, 60131 Ancona, Italy. dolla.bihs@gmail.com.ORCID 0000-0001-5063-9900
Massimiliano GasparriniDipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche (DISCO)-Sez. Biochimica, Facoltà di Medicina, Università Politecnica delle Marche, 60131 Ancona, Italy. m.gasparrini@univpm.it.ORCID 0000-0001-9738-2663
Patricia Reboredo-RodriguezDipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche (DISCO)-Sez. Biochimica, Facoltà di Medicina, Università Politecnica delle Marche, 60131 Ancona, Italy. preboredo@uvigo.es.
Piera Pia MannaDipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche (DISCO)-Sez. Biochimica, Facoltà di Medicina, Università Politecnica delle Marche, 60131 Ancona, Italy. p.piera@hotmail.it.
Jiaojiao ZhangDipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche (DISCO)-Sez. Biochimica, Facoltà di Medicina, Università Politecnica delle Marche, 60131 Ancona, Italy. zh.jojo@yahoo.com.
Leire Bravo LamasCenter for Nutrition & Health, Universidad Europea del Atlántico (UEA), 39011 Santander, Spain; leire.bravo@uneatlantico.es (L.B.L.). leire.bravo@uneatlantico.es.
Susana Martínez FlórezCenter for Nutrition & Health, Universidad Europea del Atlántico (UEA), 39011 Santander, Spain; leire.bravo@uneatlantico.es (L.B.L.). susana.martinez@uneatlantico.es.
Pablo Agudo ToyosCenter for Nutrition & Health, Universidad Europea del Atlántico (UEA), 39011 Santander, Spain; leire.bravo@uneatlantico.es (L.B.L.). pablo.agudo@uneatlantico.es.
José Luis QuilesDepartment of Physiology, Institute of Nutrition and Food Technology "Jose Mataix", Biomedical Research Centre, University of Granada, Armilla, 18100 Granada, Spain. jlquiles@ugr.es.ORCID 0000-0002-9048-9086
Francesca GiampieriDipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche (DISCO)-Sez. Biochimica, Facoltà di Medicina, Università Politecnica delle Marche, 60131 Ancona, Italy. f.giampieri@univpm.it.ORCID 0000-0002-8151-9132
Maurizio BattinoDipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche (DISCO)-Sez. Biochimica, Facoltà di Medicina, Università Politecnica delle Marche, 60131 Ancona, Italy. m.a.battino@univpm.it.ORCID 0000-0002-7250-1782
Marche Polytechnic University · ITUniversidad Europea del Atlántico · ESUniversidad de Granada · ES

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Honey is a natural substance appreciated for its therapeutic abilities since ancient times. Its content in flavonoids and phenolic acids plays a key role on human health, thanks to the high antioxidant and anti-inflammatory properties that they exert. Honey possesses antimicrobial capacity and anticancer activity against different types of tumors, acting on different molecular pathways that are involved on cellular proliferation. In addition, an antidiabetic activity has also been highlighted, with the reduction of glucose, fructosamine, and glycosylated hemoglobin serum concentration. Honey exerts also a protective effect in the cardiovascular system, where it mainly prevents the oxidation of low-density lipoproteins, in the nervous system, in the respiratory system against asthma and bacterial infections, and in the gastrointestinal system. A beneficial effect of honey can also be demonstrated in athletes. The purpose of this review is to summarize and update the current information regarding the role of honey in health and diseases.

Indexed as

AnimalsAnti-Infective AgentsAntineoplastic AgentsCardiotonic AgentsHoneyHumansHypoglycemic AgentsPhenolsSignal TransductionAnti-Infective AgentsAntineoplastic AgentsCardiotonic AgentsHypoglycemic AgentsPhenolsantimicrobial activitiesantioxidantscancerdiabetesdisease preventionhoneypolyphenols

Identifiers

PMID30208664
PMCPMC6225430
OpenAlexW2891957518

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.