Evidence map›Paper›PMID 30208636›Full record

ArticleInternational journal of molecular sciences2018

Extract of the Blood Circulation-Promoting Recipe-84 Can Protect Rat Retinas by Inhibiting the β-Catenin Signaling Pathway.

Qiu-Fang Qin, Min Liu, Gui-Hua Tian, Jian Chen, Yu-Sang Li

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.1field-weighted citation impact, top 46% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. A Systematic Study of Mechanism ofFrontiers in pharmacology · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Qiu-Fang QinDepartment of Pharmacology, School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, China. yierss@126.com.
Min LiuDepartment of Pharmacology, School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, China. byd80@163.com.
Gui-Hua TianKey Laboratory of Chinese Internal Medicine of MOE and Beijing, Beijing University of Chinese Medicine, Beijing 100700, China. rosetgh@163.com.
Jian ChenState Key Laboratory of Transducer Technology, Institute of Electronics, Chinese Academy of Sciences, Beijing 100190, China. chenjian@mail.ie.ac.cn.ORCID 0000-0003-4612-3279
Yu-Sang LiDepartment of Pharmacology, School of Pharmaceutical Sciences, South-Central University for Nationalities, Wuhan 430074, China. liys2006@mail.scuec.edu.cn.
South Central Minzu University · CNBeijing University of Chinese Medicine · CNChinese Academy of Sciences · CN

Funding

National Natural Science Foundation of China 81202942National Natural Science Foundation of China 81573887National Natural Science Foundation of China 81673711National Natural Science Foundation of China 81674050
6 · The paper itself

Abstract

Extract of the Blood Circulation-Promoting Recipe (EBR-84) from the Chinese Herbal medicine "Blood Circulation Promoting Recipe" could retard retinopathy development. This study investigated whether EBR-84 protects retinas by inhibiting the β-catenin pathway using a rat model of retinopathy and a retinal ganglion cell 5 (RGC-5) cell death model. RGC death was induced by either

Indexed as

Animalsbeta CateninCell DeathCells, CulturedCell SurvivalDrugs, Chinese HerbalMaleProtective AgentsRatsRats, Sprague-DawleyRetinaRetinal DiseasesRetinal Ganglion CellsWnt Signaling Pathwaybeta CateninDrugs, Chinese HerbalProtective AgentsEBR-84NMDAretinopathyVEGFβ-catenin

Identifiers

PMID30208636
PMCPMC6164958
OpenAlexW2890259566

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.