Evidence map›Paper›PMID 30208630›Full record

ArticleInternational journal of molecular sciences2018

Leukocyte Immunoglobulin-Like Receptors A2 and A6 are Expressed in Avian Macrophages and Modulate Cytokine Production by Activating Multiple Signaling Pathways.

Anh Duc Truong, Deivendran Rengaraj, Yeojin Hong, Ha Thi Thanh Tran, Hoang Vu Dang, Viet Khong Nguyen, Hyun S Lillehoj, Yeong Ho Hong

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. LILRB4, an immune checkpoint on myeloid cells.Blood science (Baltimore, Md.) · 2022
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Anh Duc TruongDepartment of Animal Science and Technology, Chung-Ang University, Anseong 17546, Korea. truonganhduc84@gmail.com.ORCID 0000-0002-2472-8165
Deivendran RengarajDepartment of Animal Science and Technology, Chung-Ang University, Anseong 17546, Korea. deivnedran@snu.ac.kr.
Yeojin HongDepartment of Animal Science and Technology, Chung-Ang University, Anseong 17546, Korea. lovejin5873@naver.com.
Ha Thi Thanh TranDepartment of Biochemistry and Immunology, National Institute of Veterinary Research, 86 Truong Chinh, Dong Da, Hanoi 100000, Vietnam. thanhhavty@yahoo.com.
Hoang Vu DangDepartment of Biochemistry and Immunology, National Institute of Veterinary Research, 86 Truong Chinh, Dong Da, Hanoi 100000, Vietnam. dangnivr@yahoo.com.
Viet Khong NguyenDepartment of Biochemistry and Immunology, National Institute of Veterinary Research, 86 Truong Chinh, Dong Da, Hanoi 100000, Vietnam. nguyenvietkhong@yahoo.com.
Hyun S LillehojAnimal Biosciences and Biotechnology Laboratory, Agricultural Research Services, United States Department of Agriculture, Beltsville, MD 20705, USA. Hyun.Lillehoj@ARS.USDA.GOV.
Yeong Ho HongDepartment of Animal Science and Technology, Chung-Ang University, Anseong 17546, Korea. yhong@cau.ac.kr.ORCID 0000-0002-4510-7851
Chung-Ang University · KRNational Institute of Veterinary Research · VNAgricultural Research Service · US

Funding

National Institute of Food and Agriculture #2017-6701526793Next-Generation BioGreen 21 Program, RDA of KOREA PJ01324202
6 · The paper itself

Abstract

The activating leukocyte immunoglobulin-like receptors (LILRAs) play an important role in innate immunity. However, most of the LILRA members have not been characterized in avian species including chickens. The present study is the first attempt at cloning, structural analysis and functional characterization of two LILRAs (LILRA2 and LILRA6) in chickens. Multiple sequence alignments and construction of a phylogenetic tree of chicken LILRA2 and LILRA6 with mammalian proteins revealed high conservation between chicken LILRA2 and LILRA6 and a close relationship between the chicken and mammalian proteins. The mRNA expression of

Indexed as

Immunity, InnateAmino Acid SequenceAnimalsAntigen PresentationChickensCloning, MolecularCytokinesHistocompatibility Antigens Class IHumansMacrophagesPhylogenyReceptors, ImmunologicSequence AlignmentSignal TransductionCytokinesHistocompatibility Antigens Class IReceptors, ImmunologicchickencytokineLILRAMHC class Isignaling pathway

Identifiers

PMID30208630
PMCPMC6163679
OpenAlexW2891724625

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.