Evidence map›Paper›PMID 30208419›Full record

ArticleInvestigative ophthalmology & visual science2018

Refraction and Change in Refraction Over a 20-Year Period in the Beaver Dam Eye Study.

Samantha Bomotti, Bryan Lau, Barbara E K Klein, Kristine E Lee, Ronald Klein, Priya Duggal, Alison P Klein

Open access · goldAbstract read
In one paragraph

Article in Investigative ophthalmology & visual science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.5field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 29 citations in OpenAlex.

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  4. Adult Myopia Progression.Investigative ophthalmology & visual science · 2024
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  7. IMI-Onset and Progression of Myopia in Young Adults.Investigative ophthalmology & visual science · 2023
    Review
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  9. Inflammation and retinal degenerative diseases.Neural regeneration research · 2023
    Review
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  12. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Samantha BomottiDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States.
Bryan LauDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States.
Barbara E K KleinDepartment of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, United States.
Kristine E LeeDepartment of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, United States.
Ronald KleinDepartment of Ophthalmology and Visual Sciences, University of Wisconsin School of Medicine and Public Health, University of Wisconsin-Madison, Madison, Wisconsin, United States.
Priya DuggalDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States.
Alison P KleinDepartment of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Johns Hopkins University, Baltimore, Maryland, United States.
Johns Hopkins University · USUniversity of Wisconsin–Madison · US

Funding

Identification of quantitative ocular trait genes in the Beaver Dam EyeR01EY021531 · NEI · JOHNS HOPKINS UNIVERSITY · PI DUGGAL, PRIYA, KLEIN, ALISON P · 2011 to 2013
$1.2M
Eye and Vision Genomics Training ProgramT32EY022303 · NEI · JOHNS HOPKINS UNIVERSITY · PI BEATY, TERRI H · 2013 to 2017
$799k
NEI NIH HHS R01 EY021531NEI NIH HHS T32 EY022303
6 · The paper itself

Abstract

Purpose: Hyperopic shifts in refraction have been consistently reported in adults over 40, followed by myopic shifts after age 70. Although potential factors underlying these changes in refraction in older adults have been investigated previously, the studies were restricted by the limited longitudinal data available. The authors of this study sought to better characterize the long-term trajectory of refraction in older adults using 20 years of prospective data. Methods: The impact of cohort effects on refraction over 20 years was examined. Generalized estimating equations were used to evaluate the etiologic factors underlying refraction and changes in refraction measured over a 20-year period (1988-2010) among adults over age 40 from the Beaver Dam Eye Study. Results: Only individuals with nuclear cataract experienced a myopic shift in refraction, showing a 0.25 diopter (D) decrease (95% confidence interval [CI]: -0.44 D to -0.07 D) over a five-year period. Individuals with mild and moderate nuclear sclerosis showed varying degrees of hyperopic shifts over five years (0.22 D: 95% CI: 0.20 D-0.25 D; 0.23 D: 95% CI: 0.20 D-0.27 D, respectively). Conclusions: Nuclear cataract is the primary contributor to the myopic shift among older individuals. Birth cohort effects on baseline refraction but not change in refraction were observed.

Indexed as

AdultAgedAged, 80 and overCataractFemaleFollow-Up StudiesHumansHyperopiaMaleMiddle AgedMyopiaProspective StudiesRefraction, OcularRisk FactorsTime FactorsWisconsin

Identifiers

PMID30208419
PMCPMC6133235
OpenAlexW2890526208

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.