Evidence map›Paper›PMID 30208327›Full record

ArticleCell reports2018

STIM1 and STIM2 Mediate Cancer-Induced Inflammation in T Cell Acute Lymphoblastic Leukemia.

Shella Saint Fleur-Lominy, Mate Maus, Martin Vaeth, Ingo Lange, Isabelle Zee, David Suh, Cynthia Liu, Xiaojun Wu, Anastasia Tikhonova, Iannis Aifantis and 1 more

Open access · goldAbstract read
In one paragraph

Article in Cell reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
0.7field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Review
  3. Orai1 acts as a novel CaExperimental & molecular medicine · 2026
    Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. A multiple-oscillator mechanism underlies antigen-induced CaThe Journal of biological chemistry · 2023
    Article
  9. Review
  10. Article
  11. Knockdown of Stromal Interaction Molecule 1 (Turkish journal of haematology : official journal of Turkish Society of Haematology · 2023
    Article
  12. Article
  13. Review
  14. Science CommuniCaCells · 2022
    Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Shella Saint Fleur-LominyDepartment of Medicine, New York University School of Medicine, New York, NY 10016, USA; Laura and Isaac Perlmutter Cancer Center, New York University School of Medicine, New York, NY 10016, USA.
Mate MausDepartment of Pathology, New York University School of Medicine, New York, NY 10016, USA.
Martin VaethDepartment of Pathology, New York University School of Medicine, New York, NY 10016, USA.
Ingo LangeDepartment of Pathology, New York University School of Medicine, New York, NY 10016, USA.
Isabelle ZeeDepartment of Pathology, New York University School of Medicine, New York, NY 10016, USA.
David SuhDepartment of Pathology, New York University School of Medicine, New York, NY 10016, USA.
Cynthia LiuDepartment of Pathology, New York University School of Medicine, New York, NY 10016, USA.
Xiaojun WuDepartment of Pathology, New York University School of Medicine, New York, NY 10016, USA.
Anastasia TikhonovaLaura and Isaac Perlmutter Cancer Center, New York University School of Medicine, New York, NY 10016, USA; Department of Pathology, New York University School of Medicine, New York, NY 10016, USA.
Iannis AifantisLaura and Isaac Perlmutter Cancer Center, New York University School of Medicine, New York, NY 10016, USA; Department of Pathology, New York University School of Medicine, New York, NY 10016, USA.
Stefan FeskeLaura and Isaac Perlmutter Cancer Center, New York University School of Medicine, New York, NY 10016, USA; Department of Pathology, New York University School of Medicine, New York, NY 10016, USA. Electronic address: feskes01@nyumc.org.
New York University · US

Funding

Project-005UL1TR001445 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI BREDELLA, MIRIAM ANTOINETTE, HOCHMAN, JUDITH S · 2015 to 2025
$103.5M
Vaccine FacilityP30CA016087 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI ANIRBAN MAITRA · 1985 to 2026
$83.1M
Institutional Clinical and Translational Science AwardUL1TR000038 · NCATS · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CRONSTEIN, BRUCE NEIL, HOCHMAN, JUDITH S · 2012 to 2014
$16.8M
RESEARCH IN THE PATHOGENESIS OF HEMATOLOGIC DISORDERST32HL007151 · NHLBI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI AL-HOMSI, AHMAD SAMER · 1988 to 2018
$5.9M
CRAC Channel Deficiency in Immunity to InfectionR01AI097302 · NIAID · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI FESKE, STEFAN · 2012 to 2022
$5.6M
The role of the SCF/FBW7 ubiquitin ligase complex in hematopiesis and leukemia.R01CA133379 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI AIFANTIS, IANNIS · 2009 to 2018
$3.6M
Mapping cancer micro-environments for acute leukemiaR01CA202025 · NCI · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI AIFANTIS, IANNIS, SCHWAB, SUSAN RUTH · 2016 to 2020
$2.3M
Sandy Recovery Ventana Medical Systems Discovery XTS10OD018338 · OD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI CHIRIBOGA, LUIS A · 2014 to 2014
$123k
NCATS NIH HHS UL1 TR000038NCATS NIH HHS UL1 TR001445NCI NIH HHS P30 CA016087NCI NIH HHS R01 CA133379NCI NIH HHS R01 CA202025NHLBI NIH HHS T32 HL007151NIAID NIH HHS R01 AI097302NIH HHS S10 OD018338
6 · The paper itself

Abstract

T cell acute lymphoblastic leukemia (T-ALL) is commonly associated with activating mutations in the NOTCH1 pathway. Recent reports have shown a link between NOTCH1 signaling and intracellular Ca

Indexed as

AnimalsFemaleInflammationMiceNeoplasmsPrecursor T-Cell Lymphoblastic Leukemia-LymphomaReceptor, Notch1Stromal Interaction Molecule 1Stromal Interaction Molecule 2Receptor, Notch1Stromal Interaction Molecule 1Stromal Interaction Molecule 2anemiaCa(2+)calciumCRAC channelinflammationinterferonmacrophagesNotch1STIM1STIM2T-ALLT cell acute lymphoblastic leukemia

Identifiers

PMID30208327
PMCPMC6170166
OpenAlexW2890739463

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.