Evidence map›Paper›PMID 30208294›Full record

ReviewAnnual review of genetics2018

Recent Advances in Behavioral (Epi)Genetics in Eusocial Insects.

Comzit Opachaloemphan, Hua Yan, Alexandra Leibholz, Claude Desplan, Danny Reinberg

Abstract readReview
In one paragraph

Review in Annual review of genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed.

  1. Review
  2. Article
  3. EpiBrain: the brain's epigenetic landscape in a snapshot.bioRxiv : the preprint server for biology · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Neuromodulators and neuroepigenetics of social behavior in ants.Annals of the New York Academy of Sciences · 2023
    Review
  9. Article
  10. Sex-biased expression is associated with chromatin state inbioRxiv : the preprint server for biology · 2023
    Article
  11. Article
  12. A molecular toolkit for superorganisms.Trends in genetics : TIG · 2021
    Review
  13. Article
  14. Review
  15. Article
  16. Article
  17. Review
  18. Article
  19. Epigenetic regulation of post-embryonic development.Current opinion in insect science · 2021
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Comzit OpachaloemphanDepartment of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA; email: comzit.opachaloemphan@med.nyu.edu , danny.reinberg@nyumc.org.
Hua YanDepartment of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA; email: comzit.opachaloemphan@med.nyu.edu , danny.reinberg@nyumc.org.
Alexandra LeibholzDepartment of Biology, New York University, New York, NY 10003, USA; email: al5260@nyu.edu , cd38@nyu.edu.
Claude DesplanDepartment of Biology, New York University, New York, NY 10003, USA; email: al5260@nyu.edu , cd38@nyu.edu.
Danny ReinbergDepartment of Biochemistry and Molecular Pharmacology, New York University School of Medicine, New York, NY 10016, USA; email: comzit.opachaloemphan@med.nyu.edu , danny.reinberg@nyumc.org.

Funding

Stochastic choices in the retina and optic lobesR01EY013010 · NEI · NEW YORK UNIVERSITY · PI DESPLAN, CLAUDE · 1999 to 2025
$9.1M
Aging and rejuvenation: An ant model to study the regulation of longevityR01AG058762 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI Claude Desplan, DANNY REINBERG · 2018 to 2026
$6.2M
Regulation of variable lifespan in castes of antsF32AG044971 · NIA · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI YAN, HUA · 2013 to 2015
$165k
Howard Hughes Medical Institute 2009005NEI NIH HHS R01 EY013010NIA NIH HHS F32 AG044971NIA NIH HHS R01 AG058762
6 · The paper itself

Abstract

Eusocial insects live in societies in which distinct family members serve specific roles in maintaining the colony and advancing the reproductive ability of a few select individuals. Given the genetic similarity of all colony members, the diversity of morphologies and behaviors is surprising. Social communication relies on pheromones and olfaction, as shown by mutants of orco, the universal odorant receptor coreceptor, and through electrophysiological analysis of neuronal responses to pheromones. Additionally, neurohormonal factors and epigenetic regulators play a key role in caste-specific behavior, such as foraging and caste switching. These studies start to allow an understanding of the molecular mechanisms underlying social behavior and provide a technological foundation for future studies of eusocial insects. In this review, we highlight recent findings in eusocial insects that advance our understanding of genetic and epigenetic regulations of social behavior and provide perspectives on future studies using cutting-edge technologies.

Indexed as

Social BehaviorAnimalsBehavior, AnimalEpigenesis, GeneticInsectaNeuronsPheromonesReceptors, OdorantSmellPheromonesReceptors, Odorantcaste developmentcritical periodsepigeneticsneuroplasticityodorant receptorsocial behavior

Identifiers

PMID30208294
PMCPMC6445553

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.