ArticlePloS one2018
Which obesity phenotypes predict poor health-related quality of life in adult men and women? Tehran Lipid and Glucose Study.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- Mental health and quality of life in different obesity phenotypes: a systematic review.Health and quality of life outcomes · 2022Pooled it
- Article
- Trends and economic inequalities in obesity prevalence in Ghana: a cross-sectional study spanning 2008-2022.Journal of health, population, and nutrition · 2025Article
- Obesity and overweight and associated factors among women with infertility undergoing assisted reproductive technology treatment in a low income setting.Scientific reports · 2025Article
- Quality of life and psychosocial outcomes among children with metabolically healthy and unhealthy obesity.Pediatric research · 2023Article
- Health-Related Quality of Life in Those with Persistent or Transient Obesity Phenotypes during Two Decades: Tehran Lipid and Glucose Study.Obesity facts · 2023Article
- Do lifestyle factors and quality of life differ in people with metabolically healthy and unhealthy obesity?International journal of obesity (2005) · 2022Article
- Association of Health-Related Quality of Life with Atherosclerotic Cardiovascular Disease: Lifetime Risk Pooling Project.American journal of preventive cardiology · 2021Article
- Prognostic value of different maternal obesity phenotypes in predicting offspring obesity in a family-based cohort study.BMC public health · 2021Article
- Nutritional Determinants of Quality of Life in a Mediterranean Cohort: The SUN Study.International journal of environmental research and public health · 2020Article
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Authors and funding
6 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to explore the association between different obesity phenotypes and health-related quality of life (HRQoL) among Tehranian men and women.
methodsThe participants of this study were 2880 healthy adults (aged>19 years) who participated in Tehran Lipid and Glucose Study (TLGS). To obtain socio-demographic and HRQoL information, participants were interviewed by trained interviewers and were stratified by body mass index categories and metabolic status. Dysmetabolic status was defined as having either metabolic syndrome or diabetes according to the Joint Interim Statement definition and American Diabetes Association. Poor HRQoL was defined as the first quartile of HRQoL scores and logistic regression analysis was used to compare sex-specific odds ratios.
resultsMean age of participants was 47.7±15.6 and 47.8±14.2 years in men and women respectively. The most and the least common obesity phenotypes were overweight-normal metabolic status and normal weight-dysmetabolic status, respectively. Only mean scores for physical HRQoL were significantly different among obesity phenotypes in both men and women (p<0.05). In addition, after adjusting for age, marital status, level of education, job status and physical activity, the odds of reporting poor physical HRQoL was significantly higher in men (OR: 1.960, 95% CI: 1.037-3.704; p<0.05) and women (OR: 2.887, 95% CI: 1.674-4.977; p<0.001) with obese-dysmetabolic status, compared to their counterparts with normal weight-normal metabolic status. However, except for overweight-normal metabolic women, who were less likely to report poor mental HRQoL (OR: 0.638, 95% CI: 0.415-0.981; p<0.05), none of the phenotypes were associated with poor mental HRQoL in either gender.
conclusionsCompared to those with normal weight normal metabolic status, only obese dysmetabolic individuals were more likely to report poor physical HRQoL in both genders.
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