ArticlePloS one2018
Pedigree data indicate rapid inbreeding and loss of genetic diversity within populations of native, traditional dog breeds of conservation concern.
Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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17 citing papers in PubMed.
- Dog Breeds for the Future: Theoretical Assessment of Strategies for Enhancing the Behavioural Reliability of Existing Dog Breeds, or Developing New Ideal Urban Companion Dogs.Animals : an open access journal from MDPI · 2026Review
- Unraveling IGK locus in dog breeds: IMGTNAR genomics and bioinformatics · 2026Article
- From pedigrees to practicality: an interactive tool for cat breeding.Frontiers in veterinary science · 2026Article
- Modern pedigree dogs in the United Kingdom Kennel Club: a journey through shifting population landscapes and demography.Companion animal health and genetics · 2025Article
- Purebred dogs show higher levels of genomic damage compared to mixed breed dogs.Mammalian genome : official journal of the International Mammalian Genome Society · 2024Article
- Ethical Concerns about Fashionable Dog Breeding.Animals : an open access journal from MDPI · 2024Review
- The Weight of Genetic Drift: A Pedigree-Based Evaluation of the Breton Horse Population in Brazil.Veterinary medicine international · 2024Article
- Influence of Single Layer Centrifugation with Canicoll on Semen Freezability in Dogs.Animals : an open access journal from MDPI · 2022Article
- Analyses of Genetic Diversity in the Endangered "Berrenda" Spanish Cattle Breeds Using Pedigree Data.Animals : an open access journal from MDPI · 2022Article
- White-naped mangabeys' viable insurance population within European Zoo Network.Scientific reports · 2021Article
- Examination of the efficacy of small genetic panels in genomic conservation of companion animal populations.Evolutionary applications · 2020Article
- Analysis of Genetic Diversity in the Czech Spotted Dog.Animals : an open access journal from MDPI · 2020Article
- A scan for genes associated with cancer mortality and longevity in pedigree dog breeds.Mammalian genome : official journal of the International Mammalian Genome Society · 2020Article
- The German Shorthair Pointer Dog Breed (Animals : an open access journal from MDPI · 2020Article
- Evaluation of alloreactive T cells based on the degree of MHC incompatibility using flow cytometric mixed lymphocyte reaction assay in dogs.Immunogenetics · 2019Article
- Genetic diversity and population structure of the Sapsaree, a native Korean dog breed.BMC genetics · 2019Article
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2 authors.
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Abstract
Increasing concern is directed towards genetic diversity of domestic animal populations because strong selective breeding can rapidly deplete genetic diversity of socio-economically valuable animals. International conservation policy identifies minimizing genetic erosion of domesticated animals as a key biodiversity target. We used breeding records to assess potential indications of inbreeding and loss of founder allelic diversity in 12 native Swedish dog breeds, traditional to the country, ten of which have been identified by authorities as of conservation concern. The pedigrees dated back to the mid-1900, comprising 5-11 generations and 350-66,500 individuals per pedigree. We assessed rates of inbreeding and potential indications of loss of genetic variation by measuring inbreeding coefficients and remaining number of founder alleles at five points in time during 1980-2012. We found average inbreeding coefficients among breeds to double-from an average of 0.03 in 1980 to 0.07 in 2012 -in spite of the majority of breeds being numerically large with pedigrees comprising thousands of individuals indicating that such rapid increase of inbreeding should have been possible to avoid. We also found indications of extensive loss of intra-breed variation; on average 70 percent of founder alleles are lost during 1980-2012. Explicit conservation goals for these breeds were not reflected in pedigree based conservation genetic measures; breeding needs to focus more on retaining genetic variation, and supplementary genomic analyses of these breeds are highly warranted in order to find out the extent to which the trends indicated here are reflected over the genomes of these breeds.
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