Evidence map›Paper›PMID 30207602›Full record

ArticleInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2018

Risk of stillbirth among Zambian women with a prior cesarean delivery.

Marcela C Castillo, Bellington Vwalika, Marie C D Stoner, Benjamin H Chi, Jeffrey S A Stringer, Margaret Kasaro, Andrew Kumwenda, Elizabeth M Stringer

Abstract read
In one paragraph

Article in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 90% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 2 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 3 countries.

Marcela C CastilloThe University of Texas at Austin Dell Medical School, Austin, TX, USA.
Bellington VwalikaUniversity of North Carolina School of Medicine, Chapel Hill, NC, USA.
Marie C D StonerUniversity of North Carolina Gillings School of Global Public Health, Chapel Hill, NC, USA.
Benjamin H ChiUniversity of North Carolina School of Medicine, Chapel Hill, NC, USA.
Jeffrey S A StringerUniversity of North Carolina School of Medicine, Chapel Hill, NC, USA.
Margaret KasaroUniversity of North Carolina School of Medicine, Chapel Hill, NC, USA.
Andrew KumwendaUniversity Teaching Hospital, Lusaka, Zambia.
Elizabeth M StringerUniversity of North Carolina School of Medicine, Chapel Hill, NC, USA.
University of North Carolina at Chapel Hill · USThe University of Texas at Austin · USUniversity of Zambia · ZMUniversity Teaching Hospital · ZM

Funding

Virology, Immunology, and Microbiology CoreP30AI050410 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI DAVID M. MARGOLIS · 2001 to 2026
$76.9M
Research Services CoreP2CHD050924 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI KAREN B GUZZO · 2015 to 2026
$9.6M
Fogarty Global Health Fellows Coordinating CenterR25TW009340 · FIC · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHI, BENJAMIN H. · 2012 to 2016
$6.9M
UNC Global Women’s Health FellowshipT32HD075731 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI CHI, BENJAMIN H. · 2013 to 2024
$2.4M
Mentoring new investigators in PMTCT implementation researchK24AI120796 · NIAID · UNIV OF NORTH CAROLINA CHAPEL HILL · PI Benjamin H. Chi · 2016 to 2026
$1.3M
FIC NIH HHS R25 TW009340NIAID NIH HHS K24 AI120796NIAID NIH HHS P30 AI050410NICHD NIH HHS P2C HD050924NICHD NIH HHS T32 HD075731
6 · The paper itself

Abstract

objectiveCesarean delivery (CD) may be associated with stillbirth in future pregnancies. We investigated prior CD as a risk factor for stillbirth in Lusaka, Zambia.

methodsWe conducted a retrospective cohort analysis of women with only one prior pregnancy who delivered between February 1, 2006, and May 31, 2013. We analysed data from the Zambia Electronic Perinatal System. Maternal and infant characteristics were analyzed for association with stillbirth using Pearson's χ

resultsOf 57 320 women in our cohort, 1933 (3.4%) reported a prior CD. There were 1012 (1.8%) stillbirths in the no prior CD group and 81 (4.2%) in the prior CD group (P<0.001). In multivariate models adjusting for stillbirth risk factors, prior CD was associated with antepartum (adjusted risk ratio 1.56, 95% confidence interval 1.08-2.24) and intrapartum (adjusted risk ratio 3.26, 95% confidence interval 2.40-4.42) stillbirth compared with no prior CD. The difference between groups was most apparent at 36-37 weeks' gestation (log-rank P<0.001).

conclusionPrior CD was associated with increased risk of stillbirth. Improved monitoring during labor and safe methods for induction are urgently needed in low-resource settings.

Indexed as

Perinatal DeathAdultCesarean SectionFemaleGestational AgeHumansInfant, NewbornPregnancyRetrospective StudiesRisk FactorsStillbirthYoung AdultZambiaAfricaAntepartum stillbirthIntrapartum stillbirthPrior cesarean deliveryStillbirthStillbirth risk factorsZambia

Identifiers

PMID30207602
PMCPMC6568311
OpenAlexW2890781255

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.