Evidence map›Paper›PMID 30206954›Full record

ArticleContact dermatitis2018

Adverse cutaneous reactions to skin care products on the face vary with age, but not with sex.

Li-Ning Huang, Yi-Ping Zhong, Dan Liu, Xiao-Hua Wang, Can-Yi Gong, Si Wen, Peter M Elias, Bin Yang, Mao-Qiang Man

Abstract read
In one paragraph

Article in Contact dermatitis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. A Soothing Lavender-Scented Electrospun Fibrous Eye Mask.Molecules (Basel, Switzerland) · 2024
    Article
  4. Article
  5. The link between cutaneous inflammation and cognitive impairment.Journal of the European Academy of Dermatology and Venereology : JEADV · 2022
    Review
  6. Article
  7. Observational
  8. Review
  9. Article
  10. Article
  11. Benefits of Hesperidin for Cutaneous Functions.Evidence-based complementary and alternative medicine : eCAM · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Li-Ning HuangDermatology Hospital, Southern Medical University, Guangzhou, China.
Yi-Ping ZhongDermatology Hospital, Southern Medical University, Guangzhou, China.
Dan LiuDermatology Hospital, Southern Medical University, Guangzhou, China.
Xiao-Hua WangDermatology Hospital, Southern Medical University, Guangzhou, China.
Can-Yi GongDermatology Hospital, Southern Medical University, Guangzhou, China.
Si WenDermatology Hospital, Southern Medical University, Guangzhou, China.
Peter M EliasDermatology Services, Veterans Affairs Medical Center and University of California San Francisco, San Francisco, California.
Bin YangDermatology Hospital, Southern Medical University, Guangzhou, China.
Mao-Qiang ManDermatology Hospital, Southern Medical University, Guangzhou, China.ORCID http://orcid.org/0000-0002-0957-4903
Southern Medical University · CNSan Francisco VA Medical Center · US

Funding

Pathogenesis and Therapy of Ichthyosis in Disorders of Lipid MetabolismR01AR061106 · NIAMS · NORTHERN CALIFORNIA INSTITUTE/RES/EDU · PI MAURO, THEODORA M · 2012 to 2022
$3.3M
National Institute of Arthritis, Musculoskeletal and Skin Diseases of the National Institutes of Health 2R01AR061106-06A1NIAMS NIH HHS R01 AR061106
6 · The paper itself

Abstract

backgroundAdverse skin reactions to skin care products have been increasing in recent years. However, to date, these reactions have not been well characterized.

objectiveTo describe the symptoms, clinical signs and frequency of adverse cutaneous reactions to skin care products on the face in males vs females of various ages. PATIENTS AND

methodsAll outpatients diagnosed with adverse cutaneous reactions to skin care products on the face examined by dermatologists at the Dermatology Hospital of South Medical University between November 1, 2016 and October 31, 2017, employing a questionnaire and an interview, were eligible. The associations of adverse cutaneous reactions with age and sex were analysed.

resultsA total of 433 outpatients, accounting for 0.12% of all outpatients, were assessed. Of these, 223 patients, including 204 females and 19 males, aged 4 to 75 years, were eventually diagnosed with adverse reactions to skin care products on the face. Eighty-two per cent of patients experienced pruritus, 80% showed erythema, and 48% showed visible swelling. The incidence rates of both xerosis and oedema correlated positively with age, whereas acne-like lesions were negatively associated with age, but not with sex.

conclusionsOur results indicate that pruritus, xerosis and erythema are common adverse cutaneous reactions to facial skin care products. These reactions vary with age, but not with sex. Vigorous safety testing should precede the marketing of skin care products.

Indexed as

Administration, CutaneousAdolescentAdultAgedChildCosmeticsDermatitis, Allergic ContactDermatitis, AtopicDermatologic AgentsFemaleHumansMaleMiddle AgedSkin CareYoung AdultCosmeticsDermatologic Agentsadverse reactionsageinflammationsexskin care products

Identifiers

PMID30206954
PMCPMC6234074
OpenAlexW2890257709

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.