Evidence map›Paper›PMID 30206951›Full record

ArticleJournal of clinical pharmacy and therapeutics2019

Nonmedical prescriber experiences of training and competence to report adverse drug reactions in the UK.

Andrew Thompson, Christine Randall, Justine Howard, Catrin Barker, Debbie Bowden, Paul Mooney, Agatha Munyika, Susan Smith, Munir Pirmohamed

Abstract read
In one paragraph

Article in Journal of clinical pharmacy and therapeutics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Andrew ThompsonWolfson Centre for Personalised Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.ORCID http://orcid.org/0000-0002-7087-9415
Christine RandallPharmacy Department, North West Medicines Information Centre, Liverpool, UK.
Justine HowardPharmacy Department, North West Medicines Information Centre, Liverpool, UK.
Catrin BarkerPharmacy Department, Alder Hey Children's NHS Foundation Trust, Liverpool, UK.
Debbie BowdenLiverpool Community Health NHS Trust, Liverpool, UK.
Paul MooneyPharmacy Department, Royal Liverpool and Broadgreen University Hospitals NHS Trust, Liverpool, UK.
Agatha MunyikaPharmacy Department, Mersey Care NHS Foundation Trust, Liverpool, UK.
Susan SmithMedicines Information, University Hospital Aintree, Liverpool, UK.
Munir PirmohamedWolfson Centre for Personalised Medicine, Institute of Translational Medicine, University of Liverpool, Liverpool, UK.

Funding

Medical Research Council MR/L006758/1National Institute for Health Research
6 · The paper itself

Abstract

WHAT IS KNOWN AND

objectiveAdverse drug reaction reporting in the UK is lower than expected based on epidemiological data. This study aims to explore (a) nonmedical prescribers' (NMP) confidence in identifying and reporting ADRs, (b) NMP prescribing habits and engagement with the Yellow Card Scheme (YCS) and (c) NMP desire for future training in the identification and reporting of ADRs.

methodsA survey was distributed across NMP networks in the north-west of England using Survey Monkey. Univariate analyses were performed to compare the features of reporters and nonreporters, Kruskal-Wallis H tests for comparisons within multiple subgroups and Spearman's rank correlation coefficient for response associations between answers to ordered-category questions. RESULTS AND DISCUSSION: A total of 570 responses were available for analysis, an estimated response rate of 20%. Less than half (n = 219; 38.4%) reported submitting a Yellow Card to the YCS, and the majority of those individuals have submitted five or less Yellow Cards; 28 responders reported more than five submissions. Being professionally qualified for more years (linear regression: B = 0.30, P < 0.0005; 95% CI 1.01 to 1.05) and receiving additional training support about the YCS (chi-squared: χ WHAT IS NEW AND

conclusionStrategies for improving the translation of theoretical knowledge about ADRs into practical skills in identifying ADRs, and subsequently reporting them, will be important for improving pharmacovigilance practice.

Indexed as

Clinical CompetenceAdverse Drug Reaction Reporting SystemsDrug-Related Side Effects and Adverse ReactionsEnglandHealth PersonnelHumansLinear ModelsPharmacovigilanceSurveys and QuestionnairesUnited Kingdomadverse drug reactionspatient safetypharmacovigilance

Identifiers

PMID30206951
PMCPMC6378616

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.