Evidence map›Paper›PMID 30206803›Full record

ReviewHead and neck pathology2019

Glomangiopericytoma of the Nasal Cavity with CTNNB1 p.S37C Mutation: A Case Report and Literature Review.

Michihisa Kono, Nobuyuki Bandoh, Ryosuke Matsuoka, Takashi Goto, Toshiaki Akahane, Yasutaka Kato, Hiroshi Nakano, Tomomi Yamaguchi, Yasuaki Harabuchi, Hiroshi Nishihara

Open access · hybridAbstract readCase ReportsReview
In one paragraph

Review in Head and neck pathology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 29 citations in OpenAlex.

  1. Pooled it
  2. Diagnostic Insights and Surgical Outcomes of Glomangiopericytoma: A Tertiary Center Case Series.Journal of rhinology : official journal of the Korean Rhinologic Society · 2026
    Article
  3. Article
  4. Bilateral Sinonasal Glomangiopericytoma: A Rare Case Report Misdiagnosed as Benign Nasal Polyps.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2025
    Article
  5. Article
  6. Our Experience with Sinonasal Glomangiopericytoma in North India: A Case Series.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
  7. Unveiling a Rarity: A Case Report on Glomangiopericytoma in the nasal cavity.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
    Article
  8. Glomangiopericytoma withBMJ case reports · 2023
    Article
  9. Review
  10. Article
  11. Sinonasal Glomangiopericytoma with Prolonged Postsurgical Follow-Up.Journal of neurological surgery reports · 2022
    Article
  12. Article
  13. Article
  14. Review
  15. Cold Spring Harbor molecular case studies · 2022
    Article
  16. Review
  17. Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Michihisa KonoDepartment of Otolaryngology-Head and Neck Surgery, Hokuto Hospital, Inadacho Kisen 7-5, Obihiro, 080-0833, Japan.
Nobuyuki BandohDepartment of Otolaryngology-Head and Neck Surgery, Hokuto Hospital, Inadacho Kisen 7-5, Obihiro, 080-0833, Japan. bando@hokuto7.or.jp.ORCID http://orcid.org/0000-0001-6607-8044
Ryosuke MatsuokaCenter for Diagnostic Pathology, Mita Hospital, International University of Health and Welfare, Tokyo, 108-8329, Japan.
Takashi GotoDepartment of Otolaryngology-Head and Neck Surgery, Hokuto Hospital, Inadacho Kisen 7-5, Obihiro, 080-0833, Japan.
Toshiaki AkahaneLaboratory of Cancer Medical Science, Department of Biology and Genetics, Hokuto Hospital, Inadacho Kisen 7-5, Obihiro, 080-0833, Japan.
Yasutaka KatoLaboratory of Cancer Medical Science, Department of Biology and Genetics, Hokuto Hospital, Inadacho Kisen 7-5, Obihiro, 080-0833, Japan.
Hiroshi NakanoLaboratory of Cancer Medical Science, Department of Biology and Genetics, Hokuto Hospital, Inadacho Kisen 7-5, Obihiro, 080-0833, Japan.
Tomomi YamaguchiLaboratory of Cancer Medical Science, Department of Biology and Genetics, Hokuto Hospital, Inadacho Kisen 7-5, Obihiro, 080-0833, Japan.
Yasuaki HarabuchiDepartment of Otolaryngology-Head and Neck Surgery, Asahikawa Medical University, Midorigaoka-Higashi 2-1-1-1, Asahikawa, 078-8510, Japan.
Hiroshi NishiharaKeio Cancer Center, Keio University School of Medicine, 35 Shinanomachi, Shinjukuku, Tokyo, 160-8582, Japan.
Hokuto Hospital · JPAsahikawa Medical University · JPKeio University Hospital · JPMita Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Glomangiopericytoma (GPC) is a rare mesenchymal tumor arising from the nasal cavity or paranasal sinuses. GPC was categorized as a borderline and low-malignant-potential tumor by the World Health Organization in 2005 and accounts for less than 0.5% of all sinonasal tumors. We report a case of GPC in a 74-year-old woman with a history of recurrent epistaxis and nasal obstruction. A reddish tumor was seen in the right nasal cavity. Enhanced computed tomography showed a mass lesion occupying the right nasal cavity. The tumor, which originated from the nasal septum in the olfactory fissure area, was resected with 5-mm mucosal margins by endoscopic sinus surgery. Histologic examination revealed a uniform proliferation of oval-to-short spindle-shaped cells beneath the epithelium. Immunohistologic analysis demonstrated the tumor cells were positive for α-smooth muscle actin, β-catenin and Vimentin, and negative for AE1/AE3, Bcl-2, CD34, CD117, Factor VIIIR Ag, S-100 protein, or STAT6. The percentage of Ki-67-positive cells was approximately 5%. Genetic analysis using next-generation sequencing revealed a missense mutation in the CTNNB1 gene (c.110C > G, p.S37C). While other CTNNB1 mutations have been described in GPC; this is the first report of this specific mutation. The mutation was confirmed using Sanger sequencing.

Indexed as

Agedbeta CateninFemaleHemangiopericytomaHumansMutation, MissenseNasal CavityNose Neoplasmsbeta CateninCTNNB1 protein, humanCTNNB1Endoscopic sinus surgery (ESS)Glomangiopericytoma (GPC)Next-generation sequencing (NGS)

Identifiers

PMID30206803
PMCPMC6684555
OpenAlexW2891504580

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.