Evidence map›Paper›PMID 30206694›Full record

ReviewHistochemistry and cell biology2018

Visualization of internal in situ cell structure by atomic force microscopy.

María L Segura-Valdez, Lourdes T Agredano-Moreno, Alma L Zamora-Cura, Reyna Lara-Martínez, Luis F Jiménez-García

Abstract readReview
PubMed Publisher
In one paragraph

Review in Histochemistry and cell biology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Physical energies to the rescue of damaged tissues.World journal of stem cells · 2019
    Review
  4. In focus in HCB.Histochemistry and cell biology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

María L Segura-ValdezDepartment of Cell Biology, Faculty of Sciences, National Autonomous University of Mexico (UNAM), Circuito Exterior, Ciudad Universitaria, Cd. Mx., Coyoacán, 04510, Mexico City, Mexico.
Lourdes T Agredano-MorenoDepartment of Cell Biology, Faculty of Sciences, National Autonomous University of Mexico (UNAM), Circuito Exterior, Ciudad Universitaria, Cd. Mx., Coyoacán, 04510, Mexico City, Mexico.
Alma L Zamora-CuraDepartment of Cell Biology, Faculty of Sciences, National Autonomous University of Mexico (UNAM), Circuito Exterior, Ciudad Universitaria, Cd. Mx., Coyoacán, 04510, Mexico City, Mexico.
Reyna Lara-MartínezDepartment of Cell Biology, Faculty of Sciences, National Autonomous University of Mexico (UNAM), Circuito Exterior, Ciudad Universitaria, Cd. Mx., Coyoacán, 04510, Mexico City, Mexico.
Luis F Jiménez-GarcíaDepartment of Cell Biology, Faculty of Sciences, National Autonomous University of Mexico (UNAM), Circuito Exterior, Ciudad Universitaria, Cd. Mx., Coyoacán, 04510, Mexico City, Mexico. luisfelipe_jimenez@ciencias.unam.mx.ORCID http://orcid.org/0000-0003-2368-2975

Funding

DGAPA-UNAM PAPIIT IN 217917PAPIME-DGAPA-UNAM PE213916
6 · The paper itself

Abstract

Light and electron microscopy have been used to study cell structure for many years, but atomic force microscopy is a more recent technique used to analyze cells, mainly due to the absence of techniques to prepare the samples. Isolated molecules or organelles, whole cells, and to a lesser extent in situ cell structure have been observed by different atomic force microscopy imaging modes. Here, we review efforts intended to analyze in situ the cell structures using approaches involving imaging of the surface of semithin sections of samples embedded in resin and sections prepared with an ultramicrotome. The results of such studies are discussed in relation to their implications to analyze the fine structure of organelles at the nanoscale in situ at enhanced resolution compared to light microscopy.

Indexed as

Microscopy, Atomic ForceAnimalsEpoxy ResinsHumansLymphocytesOrganellesEpoxy ResinsAtomic force microscopyCellNucleolusNucleusRNAUltramicrotome

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.