ArticleSkeletal radiology2019
Magnetic resonance imaging of the craniovertebral junction in early rheumatoid arthritis.
Article in Skeletal radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
16 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- The Influence of Reducing Disease Activity Score on Cervical Spine Deformity in Rheumatoid Arthritis: A Systematic Review.BioMed research international · 2022Pooled it
- Unilateral High-Riding Vertebral Artery Associates With the Progression of Atlantoaxial Joint Degeneration in Patients With Rheumatoid Arthritis.International journal of rheumatic diseases · 2026Observational
- Cervical Spine Involvement in Rheumatoid Arthritis: Does Joint Erosion Severity Correlate with Instability?Archives of rheumatology · 2026Article
- The assessment of atlantoaxial joint involvement in patients with rheumatoid arthritis, results from an observational "real-life" study.Scientific reports · 2023Article
- Hand and Wrist Involvement in Seropositive Rheumatoid Arthritis, Seronegative Rheumatoid Arthritis, and Psoriatic Arthritis-The Value of Classic Radiography.Journal of clinical medicine · 2023Article
- Reference values of four measures of craniocervical stability using upright dynamic magnetic resonance imaging.La Radiologia medica · 2023Article
- Radiological assessment and surgical management of cervical spine involvement in patients with rheumatoid arthritis.Rheumatology international · 2023Review
- Risk factors for the development of degenerative cervical myelopathy: a review of the literature.Neurosurgical review · 2022Review
- Radiological Evaluation of Cervical Spine Involvement in Rheumatoid Arthritis: A Cross-Sectional Retrospective Study.Journal of clinical medicine · 2021Article
- Endothelial Dysfunction and Extra-Articular Neurological Manifestations in Rheumatoid Arthritis.Biomolecules · 2021Review
- Craniocervical junction involvement in musculoskeletal diseases: an area of close collaboration between rheumatologists and radiologists.La Radiologia medica · 2020Review
- Assessment of cervical spine involvement in rheumatoid arthritis patients in the era of biologics: a real-life, cross-sectional MRI study.Rheumatology international · 2020Article
- Cervical Myelopathy in Patients Suffering from Rheumatoid Arthritis-A Case Series of 9 Patients and A Review of the Literature.Journal of clinical medicine · 2020Article
- Simple Erosion Narrowing Score of the hands as a predictor of cervical spine subluxation in rheumatoid arthritis.SA journal of radiology · 2020Article
- Radiographic scoring methods in rheumatoid arthritis and psoriatic arthritis.La Radiologia medica · 2019Review
- Musculoskeletal imaging of the inflammatory and degenerative joints: current status and perspectives.La Radiologia medica · 2019Article
Corrections and comments
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo assess the involvement of the atlantoaxial joint in patients with early rheumatoid arthritis (ERA) and to elucidate the risk profile for the individual patient. MATERIALS AND
methodsConsecutive ERA patients (disease duration < 12 months) were included in our study. A cervical spine magnetic resonance imaging (MRI) and X-rays (cervical spine, hands, wrists, and feet) were performed in all patients. The MRI features were correlated with clinical, radiological, and biochemical variables.
resultsFifty patients (13 men and 37 women) with a mean age of 58.2 years (range, 36-79 years) were included in the study. In 12 (24%) patients were detectable MRI findings suggestive of the craniovertebral junction involvement. Compared with patients without cervical involvement, the patients with atlantoaxial synovitis showed a significantly higher anti-citrullinated protein antibodies (ACPA) titer [mean 200.25 UI (SD 262.44) vs. mean 22.05 (SD 40.21) (p < 0.001)]; a worse Disease Activity Score 44 joints (DAS44) [mean 5.72 (SD 0.44) vs. mean 4.52 (SD 0.53) (p < 0.001)]; a worse Health Assessment Questionnaire Disability Index (HAQ-DI) [mean 1.55 (SD 0.37) vs. mean 1.09 (SD 0.33) (p < 0.001)], and a higher Simple Erosion Narrowing Score (SENS) [mean 15.83 (SD 4.52) vs. mean 7.71 (SD 3.43) (p < 0.001)]. The multivariate analysis revealed a meaningful relationship between atlantoaxial synovitis and ACPA, DAS44, and the presence of an erosive disease.
conclusionsThe craniovertebral junction is frequently involved in ERA patients. ACPA, high disease activity, and erosive disease at baseline are predictors of atlantoaxial involvement.
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