ArticleTomography (Ann Arbor, Mich.)2018
Dual-Energy CT-Derived Iodine Content and Spectral Attenuation Analysis of Metastatic Versus Nonmetastatic Lymph Nodes in Squamous Cell Carcinoma of the Oropharynx.
Article in Tomography (Ann Arbor, Mich.), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 23 citations in OpenAlex.
- Spectral CT and Photon-counting Detector CT: Principles and Applications in Neuroradiology.Radiology. Imaging cancer · 2026Review
- Photon counting computed tomography in head and neck squamous cell carcinoma: iodine concentration and histopathological features.Journal of cancer research and clinical oncology · 2026Article
- Integrating Radiogenomics and Machine Learning in Musculoskeletal Oncology Care.Diagnostics (Basel, Switzerland) · 2025Review
- Head and Neck Squamous Cell Carcinoma: Insights from Dual-Energy Computed Tomography (DECT).Tomography (Ann Arbor, Mich.) · 2024Review
- CT predictors of sub-centimeter occult lymph node metastases in oral cavity squamous cell carcinoma: A case-control study.The neuroradiology journal · 2024Article
- Development and Validation of a 3D Resnet Model for Prediction of Lymph Node Metastasis in Head and Neck Cancer Patients.Journal of imaging informatics in medicine · 2024Article
- Radiomics from dual-energy CT-derived iodine maps predict lymph node metastasis in head and neck squamous cell carcinoma.La Radiologia medica · 2024Article
- Iodine Density of Lymphoma, Metastatic SCCA, and Normal Cervical lymph nodes: A Comparative Analysis Based on DLSCT.F1000Research · 2024Article
- Diagnosing cervical lymph node metastasis in oral squamous cell carcinoma based on third-generation dual-source, dual-energy computed tomography.European radiology · 2023Article
- Improving radiation physics, tumor visualisation, and treatment quantification in radiotherapy with spectral or dual-energy CT.Journal of applied clinical medical physics · 2022Review
- Dual-Layer Spectral CT Imaging of Upper Aerodigestive Tract Cancer: Analysis of Spectral Imaging Parameters and Impact on Tumor Staging.AJNR. American journal of neuroradiology · 2021Article
- Multimodality oncologic evaluation of superficial neck and facial lymph nodes.La Radiologia medica · 2021Article
- Article
- Imaging biomarkers in upper gastrointestinal cancers.BJR open · 2019Review
- Dual-Energy Computed Tomography-Derived Iodine Density and Spectral Attenuation Analysis for Differentiation of Inverted Papilloma and Sinonasal Squamous Cell Carcinoma/Lymphoma.Journal of computer assisted tomographyArticle
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The presence of a single nodal metastasis has significant prognostic and treatment implications for patients with head and neck cancer. This study aims to investigate whether dual-energy computed tomography (DECT)-derived iodine content and spectral attenuation curve analysis can improve detection of nodal metastasis in oropharyngeal carcinoma. Eight patients with newly diagnosed oropharyngeal squamous cell carcinoma and pathologically proven nodal metastatic disease (n = 13 metastatic nodes; n = 16 nonmetastatic nodes) who underwent contrast-enhanced DECT of the neck were retrospectively evaluated. DECT-derived iodine content (mg/mL) and monoenergetic attenuation values at 40 keV and 100 keV were obtained via circular regions of interest within metastatic and nonmetastatic cervical lymph nodes. Iodine content was significantly lower in metastatic nodes (0.96 ± 0.28 mg/mL) than in nonmetastatic nodes (1.65 ± 0.38 mg/mL;
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