ArticleScientific reports2018
Quillaja brasiliensis saponin-based nanoparticulate adjuvants are capable of triggering early immune responses.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 46 citations in OpenAlex.
- Advances in the heterologous biosynthesis of QS saponins: a review.Microbial cell factories · 2026Review
- A comprehensive review on plant-derived bioactive saponins as promising antimicrobial agents: from bioavailability challenges, molecular mechanistic insights to therapeutic applications.Naunyn-Schmiedeberg's archives of pharmacology · 2026Review
- Evaluation ofVaccines · 2025Article
- Leaf Saponins ofPharmaceutics · 2025Review
- Intranasal Delivery ofVaccines · 2024Article
- Three immunizations with Novavax's protein vaccines increase antibody breadth and provide durable protection from SARS-CoV-2.NPJ vaccines · 2024Article
- ISCOMs/MPLA-Adjuvanted SDAD Protein Nanoparticles Induce Improved Mucosal Immune Responses and Cross-Protection in Mice.Small (Weinheim an der Bergstrasse, Germany) · 2023Article
- Article
- Immunotherapeutic nanoparticles: From autoimmune disease control to the development of vaccines.Biomaterials advances · 2022Review
- Article
- Formulation of IMXQB: Nanoparticles Based on Quillaja brasiliensis Saponins to be Used as Vaccine Adjuvants.Methods in molecular biology (Clifton, N.J.) · 2022Article
- ISCOM-like Nanoparticles Formulated withVaccines · 2021Article
- Predictive and Experimental Immunogenicity ofVaccines · 2021Article
- Recent Advances and Applications of Plant-Based Bioactive Saponins in Colloidal Multiphase Food Systems.Molecules (Basel, Switzerland) · 2021Review
- Vaccine Composition Formulated with a NovelVaccines · 2021Article
- Zika Virus Envelope Domain III Recombinant Protein Delivered With Saponin-Based Nanoadjuvant FromFrontiers in immunology · 2021Article
- Review
- Enhancement in humoral response against inactivated Newcastle disease vaccine in broiler chickens administered orally with plant-derived soyasaponin.Poultry science · 2020Article
- cGAMP/Saponin Adjuvant Combination Improves Protective Response to Influenza Vaccination by Microneedle Patch in an Aged Mouse Model.Frontiers in immunology · 2020Article
- Pathogen Molecular Pattern Receptor Agonists: Treating Cancer by Mimicking Infection.Clinical cancer research : an official journal of the American Association for Cancer Research · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 2 institutions in 2 countries.
Funding
Abstract
Commercially available saponins are extracted from Quillaja saponaria barks, being Quil A
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.