Evidence map›Paper›PMID 30206349›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2018

Genetic relatedness of Gram-negative bacteria colonizing gut and skin of neonates and mother's own milk.

Ülle Parm, Jelena Štšepetova, Imbi Eelmäe, Mirjam Merila, Mari-Liis Ilmoja, Tuuli Metsvaht, Irja Lutsar, Hiie Soeorg

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In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Collection of human bacteria at University of Tartu, Estonia.Microbiology resource announcements · 2026
    Article
  2. The Ability of Neonatal Mice to Develop Immunity toJournal of cellular immunology · 2025
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ülle ParmDepartment of Microbiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.
Jelena ŠtšepetovaDepartment of Microbiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.
Imbi EelmäePaediatric Intensive Care Unit, Clinic of Anaesthesiology and Intensive Care, Tartu University Hospital, Tartu, Estonia.
Mirjam MerilaNeonatal Unit, Children's Clinic, Tartu University Hospital, Tartu, Estonia.
Mari-Liis IlmojaDepartment of Anaesthesiology and Intensive Care, Tallinn Children's Hospital, Tallinn, Estonia.
Tuuli MetsvahtPaediatric Intensive Care Unit, Clinic of Anaesthesiology and Intensive Care, Tartu University Hospital, Tartu, Estonia.
Irja LutsarDepartment of Microbiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia.
Hiie SoeorgDepartment of Microbiology, Institute of Biomedicine and Translational Medicine, University of Tartu, Tartu, Estonia. hiie.soeorg@ut.ee.

Funding

Eesti Teadusagentuur (Estonian Research Council) IUT34-24
6 · The paper itself

Abstract

objectiveWe described colonization of mother's own milk with Gram-negative bacteria and its relationship with neonatal colonization. STUDY

designGram-negative bacteria isolated from weekly collected stool, skin and mother's own milk of hospitalized preterm (n = 49) and healthy term neonates (n = 20) were genotyped. Colonization-related factors were determined by logistic regression.

resultsGram-negative bacteria were isolated from mother's own milk of 22.4% (n = 11) and 15% (n = 3) of mothers of preterm and term neonates, respectively. According to pulsed-field gel electrophoresis genetically similar strains were present in mother's own milk and gut of 8.2% (n = 4) of mother-preterm neonate, but none of mother-term neonate pairs. In three of four late-onset sepsis caused by Gram-negative bacteria, colonization of gut, but not mother's own milk, with invasive species preceded late-onset sepsis.

conclusionsColonization of mother's own milk with Gram-negative bacteria is uncommon and transmission to neonatal gut may occur in less than one-tenth of neonate-mother pairs.

Indexed as

FecesFemaleGestational AgeGram-Negative BacteriaGram-Negative Bacterial InfectionsHumansInfant, NewbornInfant, PrematureLogistic ModelsMaleMilk, HumanMothersProspective StudiesSepsisSkin

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.