ArticleHypertension research : official journal of the Japanese Society of Hypertension2018
Microvascular endothelial function is impaired in patients with idiopathic hyperaldosteronism.
Article in Hypertension research : official journal of the Japanese Society of Hypertension, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
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Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.
- Meta-analysis of blood parameters related to lipid and glucose metabolism between two subtypes of primary aldosteronism.Journal of clinical hypertension (Greenwich, Conn.) · 2023Pooled it
- Recent progress in unraveling cardiovascular complications associated with primary aldosteronism: a succinct review.Hypertension research : official journal of the Japanese Society of Hypertension · 2024Review
- Serum Potassium Levels of 4.5 to Less Than 5.0 mmol/L Are Associated with Better Vascular Function.Journal of atherosclerosis and thrombosis · 2022Article
- A Case of a Pregnant Woman With Primary Aldosteronism and Superimposed Preeclampsia Treated With Esaxerenone.Journal of the Endocrine Society · 2022Article
- Clinical impacts of endothelium-dependent flow-mediated vasodilation assessment on primary aldosteronism.Endocrine connections · 2021Article
- Comparisons of skin microvascular changes in patients with primary aldosteronism and essential hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2020Article
- Comparison of the shortened and standard saline infusion tests for primary aldosteronism diagnostics.Hypertension research : official journal of the Japanese Society of Hypertension · 2020Article
- Serum-soluble (pro)renin receptor concentration as a biomarker for organ damage in primary aldosteronism.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Article
- Endothelial Dysfunction in Primary Aldosteronism.International journal of molecular sciences · 2019Review
- Microvascular and macrovascular endothelial function in two different types of primary aldosteronism.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Article
- Comparison of biomarkers of endothelial dysfunction and microvascular endothelial function in patients with primary aldosteronism and essential hypertension.Journal of the renin-angiotensin-aldosterone system : JRAASArticle
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aims were to evaluate the relationship between idiopathic hyperaldosteronism (IHA) and grade of vascular function in the macrovasculature and microvasculature. Vascular function, including reactive hyperemia index (RIH), flow-mediated vasodilation (FMD), and nitroglycerine-induced vasodilation (NID) were evaluated in 52 patients with IHA, 53 patients with aldosterone-producing adenoma (APA), and 52 age-, sex-, and blood pressure-matched patients with essential hypertension (EHT). Log RHI was lower in the IHA and APA groups than in the EHT group (0.54 ± 0.25 and 0.55 ± 0.23 versus 0.79 ± 0.28; P < 0.01, respectively). FMD was lower in the APA group than in the EHT group (3.4 ± 2.1% versus 4.8 ± 2.8%; P = 0.02), whereas there was no significant difference in FMD between the IHA and the APA and EHT groups. NID was lower in the APA group than in the EHT group (10.0 ± 4.5% versus 12.5 ± 5.7%; P = 0.03), whereas there was no significant difference in NID between the IHA, APA, and EHT groups. Multiple regression analysis revealed an association of log RHI with plasma aldosterone concentration (t = -2.24; P = 0.03) and an association of FMD with plasma aldosterone concentration (t = -3.07; P < 0.01). Microvascular endothelial function was impaired in patients with IHA compared with that in patients with EHT.
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Registered trials
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