Evidence map›Paper›PMID 30206187›Full record

ArticleGenetics2018

Estimating the Timing of Multiple Admixture Pulses During Local Ancestry Inference.

Paloma Medina, Bryan Thornlow, Rasmus Nielsen, Russell Corbett-Detig

Abstract read
In one paragraph

Article in Genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Paloma MedinaDepartment of Biomolecular Engineering, Genomics Institute, UC Santa Cruz, California 95064.
Bryan ThornlowDepartment of Biomolecular Engineering, Genomics Institute, UC Santa Cruz, California 95064.
Rasmus NielsenDepartments of Integrative Biology and Statistics and Museum of Natural History, University of Copenhagen, 2100 Denmark.
Russell Corbett-DetigDepartment of Biomolecular Engineering, Genomics Institute, UC Santa Cruz, California 95064 rucorbet@ucsc.edu.

Funding

Origins, Functional, and Evolutionary Consequences of Genomic VariationR35GM128932 · NIGMS · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI Russell Corbett-Detig · 2018 to 2026
$3.2M
UC Santa Cruz Training Program In Genomic SciencesT32HG008345 · NHGRI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI BROOKS, ANGELA NORIE, GREEN, RICHARD EDWARD · 2015 to 2020
$1.4M
NHGRI NIH HHS T32 HG008345NIGMS NIH HHS R35 GM128932
6 · The paper itself

Abstract

Admixture, the mixing of genetically distinct populations, is increasingly recognized as a fundamental biological process. One major goal of admixture analyses is to estimate the timing of admixture events. Whereas most methods today can only detect the most recent admixture event, here, we present coalescent theory and associated software that can be used to estimate the timing of multiple admixture events in an admixed population. We extensively validate this approach and evaluate the conditions under which it can successfully distinguish one- from two-pulse admixture models. We apply our approach to real and simulated data of

Indexed as

AnimalsDrosophila melanogasterGene FlowGenetics, PopulationModels, GeneticadmixtureDrosophila melanogasterlocal ancestry inference

Identifiers

PMID30206187
PMCPMC6218234

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.