Evidence map›Paper›PMID 30206170›Full record

ArticlemBio2018

Structural Analysis of the Interaction between the Bacterial Cell Division Proteins FtsQ and FtsB.

Danguole Kureisaite-Ciziene, Aravindan Varadajan, Stephen H McLaughlin, Marjolein Glas, Alejandro Montón Silva, Rosa Luirink, Carolin Mueller, Tanneke den Blaauwen, Tom N Grossmann, Joen Luirink and 1 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
6.0field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 57 citations in OpenAlex.

  1. In Silico Druggability Assessment ofAntibiotics (Basel, Switzerland) · 2026
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  11. Peptide-based covalent inhibitors of protein-protein interactions.Journal of peptide science : an official publication of the European Peptide Society · 2023
    Review
  12. Article
  13. Article
  14. Review
  15. Frontiers in microbiology · 2022
    Article
  16. Article
  17. Article
  18. Article
  19. FtsA acts through FtsW to promote cell wall synthesis during cell division inProceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Danguole Kureisaite-Ciziene *MRC Laboratory of Molecular Biology, Cambridge, United Kingdom.
Aravindan Varadajan *Amsterdam Institute of Molecules, Medicines and Systems, VU University, Amsterdam, The Netherlands.
Stephen H McLaughlinMRC Laboratory of Molecular Biology, Cambridge, United Kingdom.
Marjolein GlasAmsterdam Institute of Molecules, Medicines and Systems, VU University, Amsterdam, The Netherlands.
Alejandro Montón SilvaBacterial Cell Biology and Physiology, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, The Netherlands.
Rosa LuirinkAmsterdam Institute of Molecules, Medicines and Systems, VU University, Amsterdam, The Netherlands.
Carolin MuellerAmsterdam Institute of Molecules, Medicines and Systems, VU University, Amsterdam, The Netherlands.
Tanneke den BlaauwenBacterial Cell Biology and Physiology, Swammerdam Institute for Life Sciences, University of Amsterdam, Amsterdam, The Netherlands.
Tom N GrossmannAmsterdam Institute of Molecules, Medicines and Systems, VU University, Amsterdam, The Netherlands.
Joen LuirinkAmsterdam Institute of Molecules, Medicines and Systems, VU University, Amsterdam, The Netherlands s.luirink@vu.nl jyl@mrc-lmb.cam.ac.uk.
Jan LöweMRC Laboratory of Molecular Biology, Cambridge, United Kingdom s.luirink@vu.nl jyl@mrc-lmb.cam.ac.uk.ORCID 0000-0002-5218-6615
Vrije Universiteit Amsterdam · NLMRC Laboratory of Molecular Biology · GBUniversity of Amsterdam · NL

Funding

Medical Research Council U105184326Wellcome TrustWellcome Trust 202754/Z/16/Z
6 · The paper itself

Abstract

Most bacteria and archaea use the tubulin homologue FtsZ as its central organizer of cell division. In Gram-negative

Indexed as

Cell DivisionCell Cycle ProteinsCrystallography, X-RayDNA Mutational AnalysisEscherichia coliEscherichia coli ProteinsGene DeletionMembrane ProteinsProtein BindingProtein ConformationProtein DomainsProtein Interaction MappingCell Cycle ProteinsEscherichia coli ProteinsFtsB protein, E coliftsL protein, E coliFtsQ protein, E coliMembrane Proteinsbacterial cell divisionbiochemistrydivisomeFtsLFtsNmolecular microbiologyperiplasmprotein structure-functionX-ray crystallography

Identifiers

PMID30206170
PMCPMC6134095
OpenAlexW2810823843

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.