Evidence map›Paper›PMID 30206077›Full record

ArticleBMJ open2018

Neighbourhood deprivation and lung cancer risk: a nested case-control study in the USA.

Maureen Sanderson, Melinda C Aldrich, Robert S Levine, Barbara Kilbourne, Qiuyin Cai, William J Blot

Abstract read
In one paragraph

Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Maureen SandersonDepartment of Family and Community Medicine, Meharry Medical College, Nashville, Tennessee, USA.
Melinda C AldrichDepartment of Thoracic Surgery, Vanderbilt University Medical Center, Nashville, Tennessee, USA.
Robert S LevineDepartment of Family and Community Medicine, Baylor College of Medicine, Houston, Texas, USA.
Barbara KilbourneDepartment of Sociology, Tennessee State University, Nashville, Tennessee, USA.
Qiuyin CaiDivision of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.
William J BlotDivision of Epidemiology, Department of Medicine, Vanderbilt University School of Medicine, Nashville, Tennessee, USA.

Funding

Southern Community Cohort StudyR01CA092447 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BLOT, WILLIAM J., ZHENG, WEI · 2001 to 2015
$74.0M
Southern Community Cohort StudyU01CA202979 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI BLOT, WILLIAM J., SHRUBSOLE, MARTHA J. · 2016 to 2025
$22.0M
Translational Pathology CoreU54CA163069 · NCI · MEHARRY MEDICAL COLLEGE · PI BALLARD, BILLY RAY · 2011 to 2025
$18.8M
Training/Education CoreP20MD000516 · NIMHD · MEHARRY MEDICAL COLLEGE · PI JUAREZ, PAUL D · 2003 to 2013
$14.2M
Unraveling Genetic Determinants of Lung Cancer Risk in African AmericansK07CA172294 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI ALDRICH, MELINDA · 2013 to 2017
$801k
NCI NIH HHS K07 CA172294NCI NIH HHS R01 CA092447NIMHD NIH HHS P20 MD000516
6 · The paper itself

Abstract

objectivesTo examine the association between neighbourhood deprivation and lung cancer risk.

designNested case-control study.

settingSouthern Community Cohort Study of persons residing in 12 states in the southeastern USA.

participants1334 cases of lung cancer and 5315 controls. PRIMARY OUTCOME MEASURE: Risk of lung cancer.

resultsAfter adjustment for smoking status and other confounders, and additional adjustment for individual-level measures of socioeconomic status (SES), there was no monotonic increase in risk with worsening deprivation score overall or within sex and race groups. There was an increase among current and shorter term former smokers (p=0.04) but not among never and longer term former smokers. There was evidence of statistically significant interaction by sex among whites, but not blacks, in which the effect of worsening deprivation on lung cancer existed in males but not in females.

conclusionsArea-level measures of SES were associated with lung cancer risk in current and shorter term former smokers only in this population.

Indexed as

Poverty AreasAdultAgedBlack or African AmericanCase-Control StudiesEx-SmokersFemaleHumansIncidenceLung NeoplasmsMaleMiddle AgedOdds RatioProspective StudiesRisk FactorsSex Factorslung cancermulti-levelneighborhood deprivationnested case-control study

Identifiers

PMID30206077
PMCPMC6144393

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.