Evidence map›Paper›PMID 30206064›Full record

ArticleBMJ open2018

The Pain Divide: a cross-sectional analysis of chronic pain prevalence, pain intensity and opioid utilisation in England.

Adam Todd, Nasima Akhter, Joanne-Marie Cairns, Adetayo Kasim, Nick Walton, Amanda Ellison, Paul Chazot, Sam Eldabe, Clare Bambra

Abstract read
In one paragraph

Article in BMJ open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Geographical disparities in fibromyalgia severity: An Italian study.European journal of pain (London, England) · 2025
    Article
  4. Pain severity and opioid use in patients with spine-related diagnoses.Frontiers in pain research (Lausanne, Switzerland) · 2025
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  18. Living with opioids: A qualitative study with patients with chronic low back pain.Health expectations : an international journal of public participation in health care and health policy · 2020
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Adam ToddInstitute of Health and Society, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.ORCID 0000-0003-1496-9341
Nasima AkhterFuse - the UKCRC Centre for Translational Research in Public Health, Newcastle upon Tyne, UK.
Joanne-Marie CairnsInstitute of Health and Society, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Adetayo KasimFuse - the UKCRC Centre for Translational Research in Public Health, Newcastle upon Tyne, UK.
Nick WaltonInstitute of Health and Society, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Amanda EllisonWolfson Research Institute for Health and Wellbeing, Durham University, Durham, UK.
Paul ChazotWolfson Research Institute for Health and Wellbeing, Durham University, Durham, UK.
Sam EldabeInstitute of Health and Society, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.
Clare BambraInstitute of Health and Society, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.

Funding

British Heart FoundationCancer Research UKMedical Research Council MR/K02325X/1
6 · The paper itself

Abstract

objectivesOur central research question was, in England, are geographical inequalities in opioid use driven by health need (pain)? To answer this question, our study examined: (1) if there are regional inequalities in rates of chronic pain prevalence, pain intensity and opioid utilisation in England; (2) if opioid use and chronic pain are associated after adjusting for individual-level and area-level confounders.

designCross-sectional study design using data from the Health Survey for England 2011.

settingEngland. PRIMARY AND SECONDARY OUTCOME MEASURES: Chronic pain prevalence, pain intensity and opioid utilisation.

participantsParticipant data relating to chronic pain prevalence, pain intensity and opioid usage data were obtained at local authority level from the Health Survey for England 2011; in total, 5711 respondents were included in our analysis.

methodsRegional and local authority data were mapped, and a generalised linear model was then used to explore the relationships between the data. The model was adjusted to account for area-level and individual-level variables.

resultsThere were geographical variations in chronic pain prevalence, pain intensity and opioid utilisation across the English regions-with evidence of a 'pain divide' between the North and the South, whereby people in the North of England more likely to have 'severely limiting' or 'moderately limiting' chronic pain. The intensity of chronic pain was significantly and positively associated with the use of opioid analgesics.

conclusionsThere are geographical differences in chronic pain prevalence, pain intensity and opioid utilisation across England-with evidence of a 'pain divide'. Given the public health concerns associated with the long-term use of opioid analgesics-and their questionable activity in the management of chronic pain-more guidance is needed to support prescribers in the management of chronic pain, so the initiation of opioids can be avoided.

Indexed as

AdultAnalgesics, OpioidChronic PainCross-Sectional StudiesEnglandFemaleHealthcare DisparitiesHealth Status DisparitiesHumansLinear ModelsMaleMiddle AgedPain MeasurementPrevalenceSeverity of Illness IndexSocial ClassAnalgesics, Opioidhealth policypain managementpublic health

Identifiers

PMID30206064
PMCPMC6144392

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.