Evidence map›Paper›PMID 30205554›Full record

ArticleInternational journal of molecular sciences2018

Integrative Histologic and Bioinformatics Analysis of BIRC5/Survivin Expression in Oral Squamous Cell Carcinoma.

Giuseppe Troiano, Agostino Guida, Gabriella Aquino, Gerardo Botti, Nunzia Simona Losito, Silvana Papagerakis, Maria Carmela Pedicillo, Franco Ionna, Francesco Longo, Monica Cantile and 6 more

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. The development of radioresistant oral squamous carcinoma cell lines and identification of radiotherapy-related biomarkers.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023
    Article
  6. Article
  7. Article
  8. Bioinformatics analysis of BIRC5 in human cancers.Annals of translational medicine · 2022
    Article
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
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  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 4 institutions in 2 countries.

Giuseppe TroianoDepartment of Clinical and Experimental Medicine, University of Foggia, Via Rovelli 50, Foggia 71122, Italy. giuseppe.troiano@unifg.it.ORCID 0000-0001-5647-4414
Agostino GuidaMaxillofacial and ENT Surgery Department, Istituto Nazionale per lo Studio e la Cura dei Tumori, Fondazione G. Pascale, IRCCS, Naples 80131, Italy. agoguida@gmail.com.
Gabriella AquinoPathology Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori, Fondazione G. Pascale, IRCCS, Naples 80131, Italy. gabryaquino@gmail.com.
Gerardo BottiPathology Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori, Fondazione G. Pascale, IRCCS, Naples 80131, Italy. g.botti@istitutotumori.na.it.
Nunzia Simona LositoPathology Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori, Fondazione G. Pascale, IRCCS, Naples 80131, Italy. s.losito@istitutotumori.na.it.
Silvana PapagerakisDepartment of Surgery, Cancer Research Cluster, Room 4D10.2, Health Sciences Building, Saskatchewan University, Saskatoon, SKS7N5E5, Canada. silvana.papagerakis@usask.ca.
Maria Carmela PedicilloDepartment of Clinical and Experimental Medicine, University of Foggia, Via Rovelli 50, Foggia 71122, Italy. mariacarmela.pedicillo@unifg.it.
Franco IonnaMaxillofacial and ENT Surgery Department, Istituto Nazionale per lo Studio e la Cura dei Tumori, Fondazione G. Pascale, IRCCS, Naples 80131, Italy. f.ionna@istitutotumori.na.it.
Francesco LongoMaxillofacial and ENT Surgery Department, Istituto Nazionale per lo Studio e la Cura dei Tumori, Fondazione G. Pascale, IRCCS, Naples 80131, Italy. f.longo@istitutotumori.na.it.
Monica CantilePathology Unit, Istituto Nazionale per lo Studio e la Cura dei Tumori, Fondazione G. Pascale, IRCCS, Naples 80131, Italy. m.cantile@istitutotumori.na.it.
Antonio PennellaDepartment of Clinical and Experimental Medicine, University of Foggia, Via Rovelli 50, Foggia 71122, Italy. antonio.pennella@unifg.it.
Lucio Lo RussoDepartment of Clinical and Experimental Medicine, University of Foggia, Via Rovelli 50, Foggia 71122, Italy. Lucio.lorusso@unifg.it.
Giovanni Di GioiaDepartment of Clinical and Experimental Medicine, University of Foggia, Via Rovelli 50, Foggia 71122, Italy. digioia-giovanni@outlook.it.
Maria Addolorata MariggiòDepartment of Biomedical Sciences and Human Oncology, University of Bari. Piazza Giulio Cesare 11, Bari 70124, Italy. mariaaddolorata.mariggio@uniba.it.
Lorenzo Lo MuzioDepartment of Clinical and Experimental Medicine, University of Foggia, Via Rovelli 50, Foggia 71122, Italy. lorenzo.lomuzio@unifg.it.ORCID 0000-0003-4633-4893
Giuseppe PannoneDepartment of Clinical and Experimental Medicine, University of Foggia, Via Rovelli 50, Foggia 71122, Italy. giuseppe.pannone@unifg.it.
Istituto Nazionale Tumori IRCCS "Fondazione G. Pascale" · ITUniversity of Foggia · ITUniversity of Bari Aldo Moro · ITUniversity of Saskatchewan · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Survivin is a well-known protein involved in the inhibition of apoptosis in many different cancer types. The aim of this study was to perform an integrated bioinformatic and histologic analysis in order to study the expression and prognostic role of Survivin and its related gene

Indexed as

Gene Expression Regulation, NeoplasticAgedCarcinoma, Squamous CellComputational BiologyFemaleGene Regulatory NetworksHumansImmunohistochemistryMaleMiddle AgedMouth NeoplasmsPrognosisSurvivinUp-RegulationBIRC5 protein, humanSurvivinbioinformaticBIRC5immunohistochemistryoral cancerSurvivinTCGA

Identifiers

PMID30205554
PMCPMC6174346
OpenAlexW2890258302

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.