Evidence map›Paper›PMID 30205431›Full record

ArticleInternational journal of molecular sciences2018

Robotic Stereotactic Radiosurgery in Melanoma Patients with Brain Metastases under Simultaneous Anti-PD-1 Treatment.

Maike Trommer-Nestler, Simone Marnitz, Martin Kocher, Daniel Rueß, Max Schlaak, Sebastian Theurich, Michael von Bergwelt-Baildon, Janis Morgenthaler, Karolina Jablonska, Eren Celik and 2 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 5 pooled it
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 5 syntheses or guidelines pooled it, 45 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Pooled it
  6. Trial
  7. Article
  8. Assessing the Impact of Glycine onPlants (Basel, Switzerland) · 2026
    Article
  9. Observational
  10. Article
  11. Article
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. Review
  18. Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 1 country.

Maike Trommer-NestlerDepartment of Radiation Oncology and Cyberknife Center, University Hospital of Cologne, Kerpener Str. 62, 50937 Cologne, Germany. maike.trommer-nestler@uk-koeln.de.ORCID 0000-0003-2864-4273
Simone MarnitzDepartment of Radiation Oncology and Cyberknife Center, University Hospital of Cologne, Kerpener Str. 62, 50937 Cologne, Germany. simone.marnitz-schulze@uk-koeln.de.
Martin KocherCenter for Integrated Oncology (CIO Köln Bonn), University of Cologne, 50937 Cologne, Germany. martin.kocher@uk-koeln.de.ORCID 0000-0002-5674-9227
Daniel RueßCenter for Integrated Oncology (CIO Köln Bonn), University of Cologne, 50937 Cologne, Germany. daniel.ruess@uk-koeln.de.
Max SchlaakRadio Immune-Oncology Consortium (RIO), University Hospital of Cologne, 50937 Cologne, Germany. Max.Schlaak@med.uni-muenchen.de.
Sebastian TheurichRadio Immune-Oncology Consortium (RIO), University Hospital of Cologne, 50937 Cologne, Germany. Sebastian.Theurich@med.uni-muenchen.de.
Michael von Bergwelt-BaildonRadio Immune-Oncology Consortium (RIO), University Hospital of Cologne, 50937 Cologne, Germany. Michael.Bergwelt@med.uni-muenchen.de.
Janis MorgenthalerDepartment of Radiation Oncology and Cyberknife Center, University Hospital of Cologne, Kerpener Str. 62, 50937 Cologne, Germany. janis.morgenthaler@uk-koeln.de.
Karolina JablonskaDepartment of Radiation Oncology and Cyberknife Center, University Hospital of Cologne, Kerpener Str. 62, 50937 Cologne, Germany. karolina.jablonska@uk-koeln.de.
Eren CelikDepartment of Radiation Oncology and Cyberknife Center, University Hospital of Cologne, Kerpener Str. 62, 50937 Cologne, Germany. eren.celik@uk-koeln.de.
Maximilian I RugeCenter for Integrated Oncology (CIO Köln Bonn), University of Cologne, 50937 Cologne, Germany. maximilian.ruge@uk-koeln.de.
Christian BauesDepartment of Radiation Oncology and Cyberknife Center, University Hospital of Cologne, Kerpener Str. 62, 50937 Cologne, Germany. christian.baues@uk-koeln.de.ORCID 0000-0003-1733-6064
University of Cologne · DEUniversity Hospital Cologne · DEForschungszentrum Jülich · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Combination concepts of radiotherapy and immune checkpoint inhibition are currently of high interest. We examined imaging findings, acute toxicity, and local control in patients with melanoma brain metastases receiving programmed death 1 (PD-1) inhibitors and/or robotic stereotactic radiosurgery (SRS). Twenty-six patients treated with SRS alone (

Indexed as

ImmunotherapyRadiosurgeryAdultAgedAged, 80 and overBrain NeoplasmsFemaleHumansMaleMelanomaMiddle AgedProgrammed Cell Death 1 ReceptorRobotic Surgical ProceduresProgrammed Cell Death 1 Receptorbrain metastasescheckpoint inhibitionCyberknife®immunotherapymalignant melanomapseudoprogressionradioimmunotherapyrobotic stereotactic radiosurgerySRS

Identifiers

PMID30205431
PMCPMC6164579
OpenAlexW2892179556

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.