Evidence map›Paper›PMID 30205427›Full record

Trial reportNutrients2018

Carnosine Supplementation Improves Serum Resistin Concentrations in Overweight or Obese Otherwise Healthy Adults: A Pilot Randomized Trial.

Estifanos Baye, Jozef Ukropec, Maximilian P J de Courten, Aya Mousa, Timea Kurdiova, Josphin Johnson, Kirsty Wilson, Magdalena Plebanski, Giancarlo Aldini, Barbara Ukropcova and 1 more

Open access · goldAbstract readRandomized Controlled Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in Nutrients, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Histidine-Containing Dipeptides in Obesity and Cardiometabolic Health: A Systematic Scoping Review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2025
    Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Observational
  14. Review
  15. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 3 countries.

Estifanos BayeMonash Centre for Health Research and Implementation, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria 3168, Australia. estifanos.baye@monash.edu.
Jozef UkropecInstitute of Experimental Endocrinology, Biomedical Research Centre, Slovak Academy of Sciences, 84236 Bratislava, Slovakia. jozef.ukropec@gmail.com.
Maximilian P J de CourtenCentre for Chronic Disease, College of Health and Biomedicine, Victoria University, Melbourne, Victoria 3800, Australia. Maximilian.deCourten@vu.edu.au.
Aya MousaMonash Centre for Health Research and Implementation, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria 3168, Australia. aya.mousa@monash.edu.ORCID 0000-0002-7356-4523
Timea KurdiovaInstitute of Experimental Endocrinology, Biomedical Research Centre, Slovak Academy of Sciences, 84236 Bratislava, Slovakia. timea.kurdiova@savba.sk.
Josphin JohnsonMonash Centre for Health Research and Implementation, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria 3168, Australia. josphin.johnson@monash.edu.
Kirsty WilsonDepartment of Immunology and Pathology, Monash University, Melbourne, Victoria 3168, Australia. kirsty.wilson@monash.edu.
Magdalena PlebanskiDepartment of Immunology and Pathology, Monash University, Melbourne, Victoria 3168, Australia. magdalena.plebanski@monash.edu.
Giancarlo AldiniDepartment of Pharmaceutical Sciences, Università degli Studi di Milano, 20133 Milan, Italy. giancarlo.aldini@unimi.it.
Barbara UkropcovaInstitute of Experimental Endocrinology, Biomedical Research Centre, Slovak Academy of Sciences, 84236 Bratislava, Slovakia. barbara.ukropcova@gmail.com.
Barbora de CourtenMonash Centre for Health Research and Implementation, School of Public Health and Preventive Medicine, Monash University, Melbourne, Victoria 3168, Australia. barbora.decourten@monash.edu.
Monash University · AUSlovak Academy of Sciences · SKUniversity of Milan · ITVictoria University · AU

Funding

Grant Agency of the Slovak Academy of Sciences VEGA 2/191/15Slovak Research and Development Agency SRDA 15/0253
6 · The paper itself

Abstract

Adipokines play an important role in the regulation of glucose metabolism. We have previously shown that carnosine supplementation in overweight or obese non-diabetic individuals improves glucose metabolism but does not change adiponectin concentrations. However, its effect on other adipokines has not been investigated. Herein we further determined the effect of carnosine supplementation on serum adipsin, resistin and leptin. Twenty-two overweight or obese otherwise healthy adults were randomly assigned to receive either 2 g of carnosine (

Indexed as

Dietary SupplementsAdultBiomarkersCarnosineDouble-Blind MethodDown-RegulationFemaleHumansMaleMiddle AgedObesityPilot ProjectsResistinSlovakiaTreatment OutcomeBiomarkersCarnosineResistinRETN protein, humanadipokinescardiovascular diseasecarnosineobesitytype 2 diabetes

Identifiers

PMID30205427
PMCPMC6165206
OpenAlexW2889940837

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.