ArticleBrain and language2018
Quantitative assessment of grammar in amyloid-negative logopenic aphasia.
Article in Brain and language, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Dyslexia and dysgraphia of primary progressive aphasia in Chinese: A systematic review.Frontiers in neurology · 2022Pooled it
- Brain Perfusion, Atrophy, and Dopaminergic Changes in Amyloid Negative Logopenic Primary Progressive Aphasia.Scientific reports · 2025Article
- Understanding the multidimensional cognitive deficits of logopenic variant primary progressive aphasia.Brain : a journal of neurology · 2022Review
- Application of Machine Learning to Electroencephalography for the Diagnosis of Primary Progressive Aphasia: A Pilot Study.Brain sciences · 2021Article
- Western Aphasia Battery-Revised Profiles in Primary Progressive Aphasia and Primary Progressive Apraxia of Speech.American journal of speech-language pathology · 2020Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 3 institutions in 1 country.
Funding
Abstract
Logopenic primary progressive aphasia (lvPPA) typically results from underlying Alzheimer's disease, but subjects have been reported that do not show beta-amyloid (Aβ) deposition. These subjects do not differ on neurological and speech-language testing from Aβ-positive lvPPA, but they impressionistically show increased grammatical deficits. We performed a quantitative linguistic analysis of grammatical characteristics in Aβ-negative lvPPA compared to Aβ-positive lvPPA and agrammatic PPA, which is characterized by increased grammatical difficulties. Aβ-negative lvPPA used fewer function words and correct verbs but more syntactic and semantic errors compared to Aβ-positive lvPPA. These measures did not differ between Aβ-negative lvPPA and agPPA. Both lvPPA cohorts showed a higher mean length of utterance, more complex sentences, and fewer nouns than agPPA. Aβ-negative lvPPA subjects appear unique and share linguistic features with both agPPA and Aβ-positive lvPPA. Quantitative language analysis in lvPPA may be able to distinguish those with and without Aβ deposition.
Indexed as
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.