Evidence map›Paper›PMID 30205273›Full record

ArticleVirology2018

Characterizing replication kinetics and plaque production of type I feline infectious peritonitis virus in three feline cell lines.

Amornrat O'Brien, Robert C Mettelman, Aaron Volk, Nicole M André, Gary R Whittaker, Susan C Baker

Abstract read
In one paragraph

Article in Virology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.8field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 28 citations in OpenAlex.

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  13. Second round of an interlaboratory comparison of SARS-CoV2 molecular detection assays used by 45 veterinary diagnostic laboratories in the United States.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2022
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  19. Entry ofPathogens (Basel, Switzerland) · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Amornrat O'BrienDepartment of Microbiology and Immunology, Loyola University of Chicago, Stritch School of Medicine, Maywood, IL, United States.
Robert C MettelmanDepartment of Microbiology and Immunology, Loyola University of Chicago, Stritch School of Medicine, Maywood, IL, United States.
Aaron VolkDepartment of Microbiology and Immunology, Loyola University of Chicago, Stritch School of Medicine, Maywood, IL, United States.
Nicole M AndréDepartment of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, United States.
Gary R WhittakerDepartment of Microbiology and Immunology, College of Veterinary Medicine, Cornell University, Ithaca, NY, United States.
Susan C BakerDepartment of Microbiology and Immunology, Loyola University of Chicago, Stritch School of Medicine, Maywood, IL, United States. Electronic address: sbaker1@luc.edu.
Loyola University Chicago · USCornell University · US

Funding

Mechanisms of viral proteases in coronavirus replication and pathogenesisR01AI085089 · NIAID · LOYOLA UNIVERSITY CHICAGO · PI BAKER, SUSAN C., MESECAR, ANDREW D · 2010 to 2019
$6.8M
Experimental Immunology Training GrantT32AI007508 · NIAID · LOYOLA UNIVERSITY CHICAGO · PI KNIGHT, KATHERINE L. · 1997 to 2022
$4.0M
Tools for Genetic and Genomic Studies in the DogR24GM082910 · NIGMS · CORNELL UNIVERSITY · PI ACLAND, GREGORY M · 2008 to 2011
$1.5M
NIAID NIH HHS R01 AI085089NIAID NIH HHS T32 AI007508NIGMS NIH HHS R24 GM082910
6 · The paper itself

Abstract

Investigating type I feline coronaviruses (FCoVs) in tissue culture is critical for understanding the basic virology, pathogenesis, and virus-host interactome of these important veterinary pathogens. This has been a perennial challenge as type I FCoV strains do not easily adapt to cell culture. Here we characterize replication kinetics and plaque formation of a model type I strain FIPV Black in Fcwf-4 cells established at Cornell University (Fcwf-4 CU). We determined that maximum virus titers (>10

Indexed as

AnimalsCatsCell LineCoronavirus, FelineViral Plaque AssayVirus CultivationVirus ReplicationAK-D cellsFcwf-4 cellsFeline coronavirusFeline macrophage-like cell lineFIPVPlaque assay

Identifiers

PMID30205273
PMCPMC6483087
OpenAlexW2891259482

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.