Evidence map›Paper›PMID 30205186›Full record

ArticleThe Journal of allergy and clinical immunology2019

Signal transducer and activator of transcription 5B deficiency due to a novel missense mutation in the coiled-coil domain.

Meghan J Acres, Florian Gothe, Angela Grainger, Andrew J Skelton, David J Swan, Joseph D P Willet, Suzy Leech, Sonya Galcheva, Violeta Iotova, Sophie Hambleton and 1 more

Abstract readCase ReportsLetter
In one paragraph

Article in The Journal of allergy and clinical immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Infections in Inborn Errors of STATs.Pathogens (Basel, Switzerland) · 2024
    Review
  5. Review
  6. Review
  7. Review
  8. Genetic causes of growth hormone insensitivity beyond GHR.Reviews in endocrine & metabolic disorders · 2021
    Review
  9. IL-2 Signaling Axis Defects: How Many Faces?Frontiers in pediatrics · 2021
    Review
  10. Review
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Meghan J AcresPrimary Immunodeficiency Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
Florian GothePrimary Immunodeficiency Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Department of Pediatrics, Dr von Hauner Children's Hospital, Ludwig-Maximilians-Universität München, Munich, Germany.
Angela GraingerPrimary Immunodeficiency Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
Andrew J SkeltonBioinformatics Support Unit, Newcastle University, Newcastle upon Tyne, United Kingdom.
David J SwanPrimary Immunodeficiency Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
Joseph D P WilletPrimary Immunodeficiency Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
Suzy LeechGreat North Children's Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom.
Sonya GalchevaDepartment of Pediatrics, Medical University - Varna, Pediatric Endocrinology, University Hospital "St Marina", Varna, Bulgaria.
Violeta IotovaDepartment of Pediatrics, Medical University - Varna, Pediatric Endocrinology, University Hospital "St Marina", Varna, Bulgaria.
Sophie HambletonPrimary Immunodeficiency Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom; Great North Children's Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom.
Karin R EngelhardtPrimary Immunodeficiency Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom. Electronic address: karin.engelhardt@newcastle.ac.uk.

Funding

Wellcome Trust 207556/Z/17/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Mutation, MissenseAdolescentHumansMaleProtein DomainsSTAT5 Transcription FactorSTAT5B protein, humanSTAT5 Transcription Factor

Identifiers

PMID30205186
PMCPMC6320259

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.