Evidence map›Paper›PMID 30205156›Full record

ReviewThe Journal of steroid biochemistry and molecular biology2019

The serum vitamin D metabolome: What we know and what is still to discover.

Robert C Tuckey, Chloe Y S Cheng, Andrzej T Slominski

Open access · greenAbstract readReview
In one paragraph

Review in The Journal of steroid biochemistry and molecular biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 139 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
139citing papers in PubMed, 1 pooled it
11.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

139 citing papers in PubMed, 1 synthesis or guideline pooled it, 235 citations in OpenAlex.

  1. Pooled it
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  7. Review
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  13. Too much vitamin D? a drug safety review.Reviews in endocrine & metabolic disorders · 2026
    Review
  14. Review
  15. Article
  16. Vitamin D and Kawasaki disease.Frontiers in pharmacology · 2026
    Review
  17. Article
  18. 1,24,25(OH)Scientific reports · 2025
    Article
  19. Article
  20. Article

79 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Robert C TuckeySchool of Molecular Sciences, The University of Western Australia, Perth, WA, 6009, Australia. Electronic address: robert.tuckey@uwa.edu.au.
Chloe Y S ChengSchool of Molecular Sciences, The University of Western Australia, Perth, WA, 6009, Australia.
Andrzej T SlominskiDepartment of Dermatology, University of Alabama at Birmingham, AL, 35294, USA; Comprehensive Cancer Center Cancer Chemoprevention Program, University of Alabama at Birmingham, AL, 35294, USA; VA Medical Center, Birmingham, AL, 35294, USA.
The University of Western Australia · AUUniversity of Alabama at Birmingham · US

Funding

Mechanism of action and function of novel secosteroid 20(OH)D3 in the skinR01AR073004 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI ANDRZEJ T SLOMINSKI · 2018 to 2026
$2.9M
Significance of metabolic activation of lumisterol in the skinR01AR071189 · NIAMS · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI SLOMINSKI, ANDRZEJ T · 2017 to 2021
$1.6M
Role of Exogenous Melatonin in Skin BiologyR01AR056666 · NIAMS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI SLOMINSKI, ANDRZEJ T · 2011 to 2015
$1.6M
Mechanism of action of 20-hydroxyvitamin D3 in dermal fibroblastsR21AR066505 · NIAMS · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI SLOMINSKI, ANDRZEJ T · 2014 to 2015
$355k
CYP11A1-derived secosteroids as therapeutic agents in UVB induced skin cancerI01BX004293 · VA · BIRMINGHAM VA MEDICAL CENTER · PI SLOMINSKI, ANDRZEJ T · 2019 to 2025
–
BLRD VA I01 BX004293NIAMS NIH HHS R01 AR056666NIAMS NIH HHS R01 AR071189NIAMS NIH HHS R01 AR073004NIAMS NIH HHS R21 AR066505
6 · The paper itself

Abstract

Vitamin D, referring to the two forms, D2 from the diet and D3 primarily derived from phototransformation in the skin, is a prohormone important in human health. The most hormonally active form, 1α,25-dihydroxyvitamin D (1α,25(OH)

Indexed as

MetabolomeAnimalsCholesterol Side-Chain Cleavage EnzymeChromatography, LiquidHumansMetabolomicsTandem Mass SpectrometryVitamin DVitamin D3 24-HydroxylaseVitaminsCholesterol Side-Chain Cleavage EnzymeVitamin DVitamin D3 24-HydroxylaseVitamins25-Hydroxyvitamin D3Cytochrome P450LC/MS/MSMetabolomeVitamin D

Identifiers

PMID30205156
PMCPMC6342654
OpenAlexW2891847712

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.