ArticleNucleic acids research1986
Expression strategies of the yeast retrotransposon Ty: a short sequence directs ribosomal frameshifting.
Article in Nucleic acids research, 1986. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
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Who cites it
33 citing papers in PubMed, 70 citations in OpenAlex.
- Comprehensive analysis of yeast +1 ribosomal frameshifting unveils a novel stimulator supporting two distinct frameshifting mechanisms.Nucleic acids research · 2025Article
- Ribosomal frameshifting and transcriptional slippage: From genetic steganography and cryptography to adventitious use.Nucleic acids research · 2016Review
- Article
- Host co-factors of the retrovirus-like transposon Ty1.Mobile DNA · 2012Article
- Control of gag-pol gene expression in the Candida albicans retrotransposon Tca2.BMC molecular biology · 2007Article
- Construction and testing of a bacterial luciferase reporter gene system for in vivo measurement of nonsense suppression in Streptomyces.Folia microbiologica · 2006Article
- Frameshift signal transplantation and the unambiguous analysis of mutations in the yeast retrotransposon Ty1 Gag-Pol overlap region.Journal of virology · 2001Article
- Genome-wide bioinformatic and molecular analysis of introns in Saccharomyces cerevisiae.RNA (New York, N.Y.) · 1999Article
- Programmed translational frameshifting.Microbiological reviews · 1996Review
- Expression vectors for the construction of hybrid Ty-VLPs.Molecular biotechnology · 1994Article
- In vitro measurement of translation accuracy of ribosomes isolated from streptomycin-resistant mutant of Streptomyces granaticolor.Folia microbiologica · 1994Article
- Two cis-acting signals control ribosomal frameshift between human T-cell leukemia virus type II gag and pro genes.Journal of virology · 1993Article
- Expression of functional hepatitis B virus polymerase in yeast reveals it to be the sole viral protein required for correct initiation of reverse transcription.Proceedings of the National Academy of Sciences of the United States of America · 1993Article
- Ribosomal frameshifting in plants: a novel signal directs the -1 frameshift in the synthesis of the putative viral replicase of potato leafroll luteovirus.The EMBO journal · 1992Article
- Translational suppression in retroviral gene expression.Advances in virus research · 1992Review
- The population biology and evolutionary significance of Ty elements in Saccharomyces cerevisiae.Genetica · 1992Review
- Proteolytic processing of pol-TYB proteins from the yeast retrotransposon Ty1.Journal of virology · 1991Article
- Evidence that less-than-full-length pol gene products are functional in hepadnavirus DNA synthesis.Journal of virology · 1991Article
- Article
- Eucaryotic codes.Experientia · 1990Review
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The Ty element of yeast is a member of a class of eukaryotic transposons which bear a striking resemblance to retroviral proviruses in their structure and expression strategies (1,2). A direct comparison can be drawn between the production of a fusion protein encoded by Ty, resulting from a frameshift event which fuses two out-of-phase open reading frames TYA and TYB, and the production of Pr180gag-pol in a retrovirus such as Rous Sarcoma Virus (RSV) (3,4). We present data which shows, definitively, that RNA splicing is not responsible for the frameshift in Ty. By in vitro mutation of a class I element, Ty1-15, we demonstrate that 31 nucleotides contained within the region where the TYA and TYB open reading frames overlap direct the frameshift. Within this short sequence there is a region of homology with a class II element which we show is also able to frameshift.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.