ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2019
Clostridioides (Formerly Clostridium) difficile Infection During Hospitalization Increases the Likelihood of Nonhome Patient Discharge.
Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Economic Impact of Recurrent Clostridioides difficile Infection in the USA: A Systematic Literature Review and Cost Synthesis.Advances in therapy · 2023Pooled it
- Body mass index and risk of clostridioides difficile infection: a systematic review and meta-analysis.Infection · 2022Pooled it
- Role of the skilled nursing facility in Clostridioides difficile infection transitions of care: A retrospective cohort study of US hospitals.American journal of infection control · 2026Article
- Retrospective, propensity score--matched study examining the relationship between frailty and Clostridioides difficile infection in a national cohort of US veterans.American journal of infection control · 2024Article
- Reduced Vancomycin Susceptibility inOpen forum infectious diseases · 2024Article
- Interaction of Clostridioides difficile infection with frailty and cognition in the elderly: a narrative review.European journal of medical research · 2023Review
- Increased Incidence and Risk of Septicemia and Urinary Tract Infection AfterOpen forum infectious diseases · 2023Article
- Costs Attributable to Clostridioides difficile Infection Based on the Setting of Onset.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2023Article
- Impact of the Introduction of a Two-Step Laboratory Diagnostic Algorithm in the Incidence and Earlier Diagnosis ofMicroorganisms · 2022Article
- Transitions of care inTherapeutic advances in gastroenterology · 2022Review
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- Assessment of Kidney Injury as a Severity Criteria forOpen forum infectious diseases · 2020Article
- GABAergic but not Antidepressant Medications Increase Risk forOpen forum infectious diseases · 2020Article
- Real-world Experience of Bezlotoxumab for Prevention ofOpen forum infectious diseases · 2020Article
- Eosinopenia and Binary Toxin Increase Mortality in Hospitalized Patients WithOpen forum infectious diseases · 2020Article
- Review
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Authors and funding
7 authors.
Funding
Abstract
backgroundClostridioides (formerly Clostridium) difficile infection (CDI) is associated with significant morbidity and mortality, including frequent hospitalizations. However, the impact of CDI after hospital discharge is poorly understood. The purpose of this study was to assess patient discharge disposition and understand CDI-related risk factors for nonhome discharge.
methodsUsing a nationally representative database of Veterans Health Administration (VHA) patients (2003-2014) and a validation database from hospitalized non-VHA patients in Houston, Texas, admission and discharge disposition was obtained for patients with CDI and matched controls. Incidence of and clinical/microbiologic risk factors for nonhome discharge were assessed using these databases.
resultsA total of 15173 VHA patients with CDI and 48599 non-CDI control patients originally admitted from the community were included. Significantly more patients with CDI were discharged to a nonhome location compared with controls (18% vs 8%; P < .0001), most commonly hospice/death (12%) or nursing home/long-term care facility (6%). Results were confirmed using a propensity-matched analysis and a validation cohort of 1941 hospitalized patients with CDI in Houston, Texas. Age, comorbidities, severe CDI, and ribotypes F027, F001, and F053-163 were associated with a nonhome discharge (P < .05 for all).
conclusionsHospitalized patients with CDI frequently required a higher level of medical care residence at discharge compared with non-CDI patients. Risk factors for discharge to a higher level of care included CDI disease severity and variables associated with recurrent CDI.
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