Evidence map›Paper›PMID 30204830›Full record

ArticleMemorias do Instituto Oswaldo Cruz2018

Comparative genomics reveals diverse capsular polysaccharide synthesis gene clusters in emerging Raoultella planticola.

Yao-Ting Huang, Wei-Yao Chuang, Bing-Ching Ho, Zong-Yen Wu, Rita C Kuo, Mengwei Ko, Po-Yu Liu

Open access · diamondAbstract readComparative Study
In one paragraph

Article in Memorias do Instituto Oswaldo Cruz, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 56% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Comparative Genomics Reveals Pathogenicity-Related Loci inThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale · 2020
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 2 countries.

Yao-Ting HuangNational Chung Cheng University, Department of Computer Science and Information Engineering, Chia-Yi, Taiwan.
Wei-Yao ChuangNational Chung Cheng University, Department of Computer Science and Information Engineering, Chia-Yi, Taiwan.
Bing-Ching HoNational Taiwan University Hospital, Department of Clinical Laboratory Sciences and Medical Biotechnology, Taipei, Taiwan.
Zong-Yen WuUS Department of Energy Joint Genome Institute, Walnut Creek, CA, USA.
Rita C KuoUS Department of Energy Joint Genome Institute, Walnut Creek, CA, USA.
Mengwei KoUniversity of California, Division of Oral Biology and Oral Medicine, School of Dentistry and Medicine, The Jane and Jerry Weintraub Center for Reconstructive Biotechnology, Los Angeles, CA, USA.
Po-Yu LiuShu-Zen Junior College of Medicine and Management, Department of Nursing, Kaohsiung City, Taiwan.
National Chung Cheng University · TWJoint Genome Institute · USNational Chung Hsing University · TWNational Taiwan University Hospital · TWTaichung Veterans General Hospital · TWUniversity of California, Los Angeles · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Raoultella planticola is an emerging zoonotic pathogen that is associated with rare but life-threatening cases of bacteremia, biliary tract infections, and urinary tract infections. Moreover, increasing antimicrobial resistance in the organism poses a potential threat to public health. In spite of its importance as a human pathogen, the genome of R. planticola remains largely unexplored and little is known about its virulence factors. Although lipopolysaccharides has been detected in R. planticola and implicated in the virulence in earlier studies, the genetic background is unknown. Here, we report the complete genome and comparative analysis of the multidrug-resistant clinical isolate R. planticola GODA. The complete genome sequence of R. planticola GODA was sequenced using single-molecule real-time DNA sequencing. Comparative genomic analysis reveals distinct capsular polysaccharide synthesis gene clusters in R. planticola GODA. In addition, we found bla TEM-57 and multiple transporters related to multidrug resistance. The availability of genomic data in open databases of this emerging zoonotic pathogen, in tandem with our comparative study, provides better understanding of R. planticola and the basis for future work.

Indexed as

Bacterial CapsulesEnterobacteriaceaeGenes, BacterialGenome, BacterialPolysaccharides, BacterialPolysaccharides, Bacterial

Identifiers

PMID30204830
PMCPMC6135345
OpenAlexW2889156528

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.