Evidence map›Paper›PMID 30204745›Full record

ArticleSexually transmitted diseases2018

Risk Factors for Oral Human Papillomavirus Infection Among Young Men Who Have Sex With Men-2 Cities, United States, 2012-2014.

Sara E Oliver, Pamina M Gorbach, Beau Gratzer, Martin Steinau, Tom Collins, Adam Parrish, Peter R Kerndt, Richard A Crosby, Elizabeth R Unger, Lauri E Markowitz and 1 more

Open access · greenAbstract read
In one paragraph

Article in Sexually transmitted diseases, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 3 pooled it
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 3 syntheses or guidelines pooled it, 23 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 1 country.

Sara E OliverFrom the Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA.
Pamina M GorbachFielding School of Public Health, University of California at Los Angeles, Los Angeles, CA.
Beau GratzerHoward Brown Health, Chicago, IL.
Martin SteinauDivision of Global HIV and TB, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA.
Tom CollinsCollege of Public Health, University of Kentucky, Lexington, KY.
Adam ParrishCollege of Public Health, University of Kentucky, Lexington, KY.
Peter R KerndtDivision of Global HIV and TB, Center for Global Health, Centers for Disease Control and Prevention, Atlanta, GA.
Richard A CrosbyCollege of Public Health, University of Kentucky, Lexington, KY.
Elizabeth R UngerDivision of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, GA.
Lauri E MarkowitzFrom the Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA.
Elissa MeitesFrom the Division of Viral Diseases, National Center for Immunization and Respiratory Diseases, Centers for Disease Control and Prevention, Atlanta, GA.
Centers for Disease Control and Prevention · USUniversity of Kentucky · USCenter for Global Health · USHoward Brown Health Center · USNational Center for Emerging and Zoonotic Infectious Diseases · USNational Center for Immunization and Respiratory Diseases · USUniversity of California, Los Angeles · US

Funding

Intramural CDC HHS CC999999
6 · The paper itself

Abstract

backgroundMen who have sex with men (MSM) are at risk for cancers attributable to human papillomavirus (HPV), including oropharyngeal cancer. Human papillomavirus vaccination is recommended for US MSM through age 26 years. Oral HPV infection is associated with oropharyngeal cancer. We determined oral HPV prevalence and risk factors among young MSM.

methodsThe Young Men's HPV study enrolled MSM aged 18 through 26 years from clinics in Chicago and Los Angeles during 2012 to 2014. Participants self-reported demographics, sexual behaviors, vaccination and human immunodeficiency virus (HIV) status. Self-collected oral rinse specimens were tested for HPV DNA (37 types) by L1-consensus PCR. We calculated adjusted prevalence ratios (aPR) and 95% confidence intervals (CI) for risk factors associated with oral HPV among participants not previously vaccinated.

resultsOral HPV was detected in 87 (9.4%) of 922; 9-valent vaccine types were detected in 37 (4.0%) of 922. Among HIV-positive participants, 17 (19.3%) of 88 had oral HPV detected. Oral HPV was more prevalent among those reporting first sex at 18 years of age or younger (aPR, 2.44; 95% CI, 1.16-5.12); HIV infection (aPR, 1.99; 95% CI, 1.14-3.48); greater than 5 sex partners within the past month (aPR, 1.93; 95% CI, 1.13-3.31); performing oral sex on greater than 5 partners within the last 3 months (aPR, 1.87; 95% CI, 1.12-3.13); and having greater than 5 male sex partners within the last 3 months (aPR, 1.76; 95% CI, 1.08-2.87). Only 454 (49.2%) of 922 were aware that HPV can cause oropharyngeal cancers.

conclusionsMany oral HPV infections were with types targeted by vaccination. Oral HPV infections were significantly associated with HIV and sexual behaviors. Fewer than half of participants were aware that HPV could cause oropharyngeal cancer.

Indexed as

AdolescentAdultCross-Sectional StudiesGender IdentityHIV InfectionsHomosexuality, MaleHumansMaleMouthOropharyngeal NeoplasmsPapillomaviridaePapillomavirus InfectionsPapillomavirus VaccinesPrevalenceRisk FactorsSexual BehaviorPapillomavirus Vaccines

Identifiers

PMID30204745
PMCPMC6148358
OpenAlexW2802716113

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.