Evidence map›Paper›PMID 30204720›Full record

ArticleJournal of acquired immune deficiency syndromes (1999)2018

Brief Report: Integration of PrEP Services Into Routine Antenatal and Postnatal Care: Experiences From an Implementation Program in Western Kenya.

Jillian Pintye, John Kinuthia, D Allen Roberts, Anjuli D Wagner, Kenneth Mugwanya, Felix Abuna, Harison Lagat, George Owiti, Carol E Levin, Ruanne V Barnabas and 2 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of acquired immune deficiency syndromes (1999), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed, 1 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 1 synthesis or guideline pooled it, 89 citations in OpenAlex.

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2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Jillian PintyeDepartment of Global Health, University of Washington, Seattle, WA.
John KinuthiaDepartment of Global Health, University of Washington, Seattle, WA.
D Allen RobertsDepartment of Epidemiology, University of Washington, Seattle, WA.
Anjuli D WagnerDepartment of Global Health, University of Washington, Seattle, WA.
Kenneth MugwanyaDepartment of Global Health, University of Washington, Seattle, WA.
Felix AbunaUniversity of Washington-Kenya, Nairobi, Kenya.
Harison LagatUniversity of Washington-Kenya, Nairobi, Kenya.
George OwitiUniversity of Washington-Kenya, Nairobi, Kenya.
Carol E LevinDepartment of Global Health, University of Washington, Seattle, WA.
Ruanne V BarnabasDepartment of Global Health, University of Washington, Seattle, WA.
Jared M BaetenDepartment of Global Health, University of Washington, Seattle, WA.
Grace John-StewartDepartment of Global Health, University of Washington, Seattle, WA.
University of Washington · USUniversity of Nairobi · KE

Funding

University of Washington/Fred Hutch Center for AIDS ResearchP30AI027757 · NIAID · UNIVERSITY OF WASHINGTON · PI Judith Tsui · 1988 to 2026
$104.9M
University of Washington Medical Scientist Training Program: MD/PhDT32GM007266 · NIGMS · UNIVERSITY OF WASHINGTON · PI HORWITZ, MARSHALL S. · 1985 to 2023
$30.4M
A differentiated care model to improve the efficiency of PrEP delivery in KenyaR00MH118134 · NIMH · UNIVERSITY OF WASHINGTON · PI MUGWANYA, KENNETH KIGGUNDU · 2019 to 2021
$743k
A differentiated care model to improve the efficiency of PrEP delivery in KenyaK99MH118134 · NIMH · UNIVERSITY OF WASHINGTON · PI MUGWANYA, KENNETH KIGGUNDU · 2018 to 2018
$123k
Adherence to Pre-Exposure Prophylaxis for HIV Prevention in PregnancyF32NR017125 · NINR · UNIVERSITY OF WASHINGTON · PI PINTYE, JILLIAN · 2017 to 2017
$61k
NIAID NIH HHS P30 AI027757NIGMS NIH HHS T32 GM007266NIMH NIH HHS K99 MH118134NIMH NIH HHS R00 MH118134NINR NIH HHS F32 NR017125
6 · The paper itself

Abstract

backgroundProgrammatic approaches for delivering pre-exposure prophylaxis (PrEP) to pregnant and postpartum women in settings with high HIV burden are undefined. The PrEP Implementation for Young Women and Adolescents (PrIYA) Program developed approaches for delivering PrEP in maternal child health (MCH) clinics.

methodsUnder the PrIYA Program, nurse-led teams worked with MCH staff at 16 public, faith-based, and private facilities in Kisumu, Kenya, to determine optimal clinic flow for PrEP integration into antenatal care (ANC) and postnatal care (PNC). A program-dedicated nurse facilitated integration. HIV-uninfected women were screened for behavioral risk factors; same-day PrEP was provided to interested and medically eligible women. PrEP and MCH services were evaluated using standardized flow mapping and time-and-motion surveys.

resultsClinics developed 2 approaches for integrating PrEP delivery within ANC/PNC: (1) co-delivery: ANC/PNC and PrEP services delivered by same MCH nurse or (2) sequential services: PrEP services after ANC/PNC by a PrEP-specialized nurse. Three clinics selected co-delivery and 13 sequential services, based on patient volume and space availability. Overall, 86 ANC/PNC visits were observed. Clients who initiated PrEP took a median of 18 minutes (interquartile range 15-26) for PrEP-related activities (risk assessment, PrEP counseling, creatinine testing, dispensation, and documentation) in addition to other routine ANC/PNC activities. For clients who declined PrEP, an additional 13 minutes (interquartile range 7-15) was spent on PrEP-related risk assessment and counseling.

conclusionsPrEP delivery within MCH used co-delivery or sequential approaches. The moderate additional time burden for PrEP initiation in MCH would likely decline with community awareness and innovations such as group/peer counseling or expedited dispensing.

Indexed as

AdolescentChemopreventionDisease Transmission, InfectiousFemaleHIV InfectionsHumansKenyaPostnatal CarePre-Exposure ProphylaxisPrenatal CareYoung Adult

Identifiers

PMID30204720
PMCPMC6500722
OpenAlexW2977398760

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.