Evidence map›Paper›PMID 30203992›Full record

ArticleEnvironmental health perspectives2018

Fine and Coarse Particulate Matter Exposures and Associations with Acute Cardiac Events among Participants in a Telemedicine Service: A Case-Crossover Study.

Ronit Nirel, Sara D Adar, Uri Dayan, Bella Vakulenko-Lagun, Michal Golovner, Ilan Levy, Zvi Alon, Alon Peretz

Open access · diamondAbstract read
In one paragraph

Article in Environmental health perspectives, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 2 countries.

Ronit Nirel1 Department of Statistics, Hebrew University of Jerusalem , Jerusalem, Israel.
Sara D Adar2 Department of Epidemiology, University of Michigan , Ann Arbor, Michigan, USA.
Uri Dayan3 Department of Geography, Hebrew University of Jerusalem , Jerusalem, Israel.
Bella Vakulenko-Lagun1 Department of Statistics, Hebrew University of Jerusalem , Jerusalem, Israel.
Michal Golovner4 SHL Telemedicine Israel , Tel Aviv, Israel.
Ilan Levy5 Center of Excellence in Exposure Science and Environmental Health, Technion , Haifa, Israel.
Zvi Alon1 Department of Statistics, Hebrew University of Jerusalem , Jerusalem, Israel.
Alon Peretz6 Occupational Medicine Clinic, Rabin Medical Center , Petah Tiqua, Israel.
Hebrew University of Jerusalem · ILRabin Medical Center · ILTechnion – Israel Institute of Technology · ILUniversity of Michigan · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSubclinical cardiovascular changes have been associated with ambient particulate matter (PM) exposures within hours. Although the U.S. Environmental Protection Agency continues to look for additional evidence of effects associated with sub-daily PM exposure, this information is still limited because most studies of clinical events have lacked data on the onset time of symptoms to assess rapid increased risk.

objectiveOur objective was to investigate associations between sub-daily exposures to PM and acute cardiac events using telemedicine data.

methodsWe conducted a case-crossover study among telemedicine participants [Formula: see text] of age who called a service center for cardiac-related symptoms and were transferred to a hospital in Tel Aviv and Haifa, Israel (2002-2013). Ambient [Formula: see text] and [Formula: see text] measured by monitors located in each city during the hours before the patient called with symptoms were compared with matched control periods. We investigated the sensitivity of these associations to more accurate symptom onset time and greater certainty of diagnosis.

resultsWe captured 12,661 calls from 7,617 subscribers experiencing ischemic (19%), arrhythmic (31%), or nonspecific (49%) cardiac events. PM concentrations were associated with small increases in the odds of cardiac events. For example, odds ratios for any cardiac event in association with a [Formula: see text] increase in 6-h and 24-h average [Formula: see text] were 1.008 [95% confidence interval (CI): 0.998, 1.018] and 1.006 (95% CI: 0.995, 1.018), respectively, and for [Formula: see text] were 1.003 (95% CI: 1.001, 1.006) and 1.003 (95% CI: 1.000, 1.007), respectively. Associations were stronger when using exposures matched to the call time rather than calendar date and for events with higher certainty of the diagnosis.

conclusionsOur analysis of telemedicine data suggests that risks of cardiac events in telemedicine participants [Formula: see text] of age may increase within hours of PM exposures. https://doi.org/10.1289/EHP2596.

Indexed as

Environmental ExposureAcute DiseaseAgedAged, 80 and overCardiovascular DiseasesCross-Over StudiesFemaleHumansIsraelMaleMiddle AgedParticle SizeParticulate MatterTelemedicineParticulate Matter

Identifiers

PMID30203992
PMCPMC6375393
OpenAlexW2892287913

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.