ArticlePsycho-oncology2018
Sexual dysfunction and reproductive concerns in young women with breast cancer: Type, prevalence, and predictors of problems.
Article in Psycho-oncology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06458764 (SEXCHECK - Sexual Dysfunction Check-up in Premenopausal Breast Cancer Survivors Taking Endocrine Therapy), which is not on this map. Cited by 73 papers, 5 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
SEXCHECK - Sexual Dysfunction Check-up in Premenopausal Breast Cancer Survivors Taking Endocrine Therapy: A Cross-Sectional Study
Who cites it
73 citing papers in PubMed, 5 syntheses or guidelines pooled it, 166 citations in OpenAlex.
- Pooled it
- Influencing factors of fertility concerns in cancer patients of childbearing age: a systematic review and meta-analysis.Frontiers in oncology · 2026Pooled it
- Sexual dysfunction in women with breast cancer: a systematic review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Pooled it
- Health-related quality of life in breast cancer patients in Asia: A meta-analysis and systematic review.Frontiers in oncology · 2022Pooled it
- Enhancing Self-Esteem and Body Image of Breast Cancer Women through Interventions: A Systematic Review.International journal of environmental research and public health · 2021Pooled it
- Preliminary evaluation of the acceptability, appropriateness, and feasibility of an online sexual health educational video series for breast cancer patients.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Trial
- Trial
- Starting the Conversation: randomized pilot trial of an intervention to promote effective clinical communication about sexual health for gynecologic cancer survivors.Journal of cancer survivorship : research and practice · 2024Trial
- An investigation of the effect of mindfulness-integrated cognitive behavior therapy on demoralization, body image, and sexual function in Iranian women with breast cancer: a randomized controlled trial.Journal of cancer research and clinical oncology · 2024Trial
- The role of a discussion forum within a web-based psychoeducational intervention focusing on sex and fertility-What do young adults communicate?Cancer medicine · 2023Trial
- Efficacy of a multimedia intervention in facilitating breast cancer patients' clinical communication about sexual health: Results of a randomized controlled trial.Psycho-oncology · 2021Trial
- The affect of goserelin on the QoL of women having chemotherapy for EBC: Results from the OPTION trial.Breast (Edinburgh, Scotland) · 2020Trial
- Health-related Quality of Life of Breast Cancer Survivors Attending an Exercise Intervention Study: A Five-year Follow-up.In vivo (Athens, Greece)Trial
- Sexual function and activity in young adults with a primary brain tumor-A population-based longitudinal study.Neuro-oncology practice · 2026Article
- Sexual health and REhabilitation online (SHAREonline): study protocol of an optimisation trial.BMJ open · 2026Article
- Primary care visits are higher amongst adults who report sexual dysfunction concerns after cancer treatment.Scientific reports · 2026Article
- Development and Validation of the RCAC-7: A Simplified Unisex Scale for Reproductive Concerns in Adolescent and Young Adult Cancer Survivors.Journal of gastrointestinal cancer · 2026Article
- A pilot study of a sexual health workshop for oncology staff: feasibility, impact, and gaps in addressing young adult breast cancer survivorship needs.Journal of cancer survivorship : research and practice · 2026Article
- Body image distress, self-esteem, and psychological adjustment following breast cancer surgery: a comparative and mediation analysis.Health psychology and behavioral medicine · 2026Article
- Role of depression, anxiety and stress in predicting body image disturbance; the mediating role of shame and guilt in patients with breast cancer.Journal of education and health promotion · 2026Article
13 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveA dearth of studies focusing on young women (<40 years) with breast cancer have hampered the understanding of the type, prevalence, and predictors of sexual dysfunction and reproductive concerns in this population.
methodsData were collected from 181 women (response rate = 60%) diagnosed with breast cancer approximately 2 years previously (age 21-39) using the Swedish National Quality Registry for Breast Cancer and a survey including standardized measures of sexual dysfunction, reproductive concerns, body image, and health-related quality of life. Multivariable logistic binary regression analyses were used to identify predictors of sexual dysfunction and reproductive concerns.
resultsSexual dysfunction in at least one domain was reported by 68% of the women, and a high level of reproductive concerns in at least one dimension was reported by 58%. Model results showed that current endocrine treatment was a significant predictor of dysfunction related to lubrication (OR 3.8, 95% CI 1.2-12.1) and vaginal discomfort (OR 8.7, 95% CI 1.5-51.5). Negative body image was related to satisfaction with sex life (OR 1.1, 95% CI 1.0-1.2). A high level of reproductive concerns was predicted by a wish for (additional) children in the future (OR 3.4, 95% CI 1.1-10.2) and by previous chemotherapy (OR 2.5, 95% CI 1.1-5.9).
conclusionsSexual dysfunction and reproductive concerns are common in young women with breast cancer. Current endocrine treatment, previous chemotherapy, a negative body image, and a wish for children in the future predict higher level of problems.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.