ArticleEquine veterinary journal2019
Efficacy of inhaled budesonide for the treatment of severe equine asthma.
Article in Equine veterinary journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed, 23 citations in OpenAlex.
- An in-hospital clinical trial assessing nebulized lidocaine compared to saline for treatment of asthma in horses.Journal of veterinary internal medicine · 2026Article
- Systemic absorption of triamcinolone acetonide is increased from intrasynovial versus extrasynovial sites and induces hyperglycemia, hyperinsulinemia, and suppression of the hypothalamic-pituitary-adrenal axis.Frontiers in veterinary science · 2024Article
- Decision Making in Severe Equine Asthma-Diagnosis and Monitoring.Animals : an open access journal from MDPI · 2023Review
- Review
- Inhalative Nanoparticulate CpG Immunotherapy in Severe Equine Asthma: An Innovative Therapeutic Concept and Potential Animal Model for Human Asthma Treatment.Animals : an open access journal from MDPI · 2022Review
- A CONSORT-guided, randomized, double-blind, controlled pilot clinical trial of inhaled lidocaine for the treatment of equine asthma.Canadian journal of veterinary research = Revue canadienne de recherche veterinaire · 2022Article
- Inhaled ciclesonide is efficacious and well tolerated in the treatment of severe equine asthma in a large prospective European clinical trial.Equine veterinary journal · 2021Article
- Glucocorticoid treatment in horses with asthma: A narrative review.Journal of veterinary internal medicine · 2021Review
- Nebulized dexamethasone sodium phosphate in the treatment of horses with severe asthma.Journal of veterinary internal medicine · 2021Article
- Effect of different doses of inhaled ciclesonide on lung function, clinical signs related to airflow limitation and serum cortisol levels in horses with experimentally induced mild to severe airway obstruction.Equine veterinary journal · 2019Article
- Comparative Review of Asthma in Farmers and Horses.Current allergy and asthma reports · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 2 institutions in 3 countries.
Funding
Abstract
backgroundCorticosteroids are the most potent drugs for the control of severe equine asthma, but adverse effects limit their chronic systemic administration. Inhaled medications allow for drug delivery directly into the airways, reducing the harmful effects of these drugs.
objectivesTo evaluate the efficacy of inhaled budesonide specifically formulated for the equine use and administered by a novel inhalation device in horses with severe asthma. STUDY
designExperimental studies in horses with naturally occurring asthma with cross-over, randomised, blinded experimental designs.
methodsIn Study 1, budesonide (1800 μg twice daily) administered using a novel Respimat
resultsIn Study 1, there was a marked and significant improvement in the lung function of all horses treated with budesonide and dexamethasone. Neutrophil percentages in bronchoalveolar fluid decreased in all horses treated with dexamethasone and in four of six horses treated with budesonide. Serum cortisol and blood ACTH concentrations decreased with both treatments. In Study 2, there was a significant improvement in the lung function with all dosages of budesonide, and the effects of higher dosages were comparable to those of dexamethasone. Dexamethasone and budesonide at the two higher dosages induced a significant decrease of cortisol concentrations. MAIN LIMITATIONS: The Respimat
conclusionsAdministration of budesonide with the Respimat
Indexed as
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.