Evidence map›Paper›PMID 30203312›Full record

ArticleDrugs & aging2018

Frailty Status Affects the Decision for Long-Term Anticoagulation Therapy in Elderly Patients with Atrial Fibrillation.

Panteleimon E Papakonstantinou, Natalia I Asimakopoulou, John A Papadakis, Dimitrios Leventis, Michail Panousieris, George Mentzantonakis, Ermis Hoda, Simeon Panagiotakis, Achilleas Gikas

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Article in Drugs & aging, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Panteleimon E PapakonstantinouDepartment of Internal Medicine, University Hospital of Heraklion "PAGNI", School of Medicine, University of Crete, Voutes, 71110, Heraklion, Crete, Greece. pantelispapakon@gmail.com.
Natalia I AsimakopoulouDepartment of Internal Medicine, University Hospital of Heraklion "PAGNI", School of Medicine, University of Crete, Voutes, 71110, Heraklion, Crete, Greece.
John A PapadakisDepartment of Internal Medicine, University Hospital of Heraklion "PAGNI", School of Medicine, University of Crete, Voutes, 71110, Heraklion, Crete, Greece.
Dimitrios LeventisDepartment of Internal Medicine, University Hospital of Heraklion "PAGNI", School of Medicine, University of Crete, Voutes, 71110, Heraklion, Crete, Greece.
Michail PanousierisDepartment of Internal Medicine, University Hospital of Heraklion "PAGNI", School of Medicine, University of Crete, Voutes, 71110, Heraklion, Crete, Greece.
George MentzantonakisDepartment of Internal Medicine, University Hospital of Heraklion "PAGNI", School of Medicine, University of Crete, Voutes, 71110, Heraklion, Crete, Greece.
Ermis HodaDepartment of Internal Medicine, University Hospital of Heraklion "PAGNI", School of Medicine, University of Crete, Voutes, 71110, Heraklion, Crete, Greece.
Simeon PanagiotakisDepartment of Internal Medicine, University Hospital of Heraklion "PAGNI", School of Medicine, University of Crete, Voutes, 71110, Heraklion, Crete, Greece.
Achilleas GikasDepartment of Internal Medicine, University Hospital of Heraklion "PAGNI", School of Medicine, University of Crete, Voutes, 71110, Heraklion, Crete, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundElderly patients are underrepresented in the studies concerning anticoagulation therapy (AT) in atrial fibrillation (AF), while patients' frailty status is lacking in most of the studies.

objectiveOur objective was to evaluate AT in AF elderly patients and study the effect of patients' frailty status on their long-term AT.

methodsWe conducted an observational prospective study that enrolled consecutive AF patients (≥ 75 years) who were hospitalized in the Department of Internal Medicine of the University Hospital of Heraklion, Crete, Greece from 1 June 2015 to 1 June 2016. We recorded the AT on admission and at discharge, all-cause mortality, and hospital readmission in a follow-up period of 1 year after hospital discharge. Frailty status was assessed by pre-established scores.

resultsOne hundred and four consecutive patients (49% male; median age 87 years) were enrolled, 78 (78.8%) of whom received AT at discharge. Patients who did not receive AT at discharge had a higher HEMORR

conclusionA high percentage of the elderly AF patients did not receive AT, even at discharge. Patients who did not receive AT at discharge had higher bleeding and frailty scores. In the 1-year follow-up period after hospital discharge, high all-cause mortality and a high number of hospital readmissions were recorded.

Indexed as

FrailtyAgedAged, 80 and overAnticoagulantsAtrial FibrillationFemaleHemorrhageHumansHypertensionMalePatient DischargeProspective StudiesRisk FactorsStrokeAnticoagulants

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.