Evidence map›Paper›PMID 30203149›Full record

ReviewCurrent hypertension reports2018

Catheter-Based Renal Denervation for Hypertension.

Raymond R Townsend, Paul A Sobotka

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current hypertension reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Beyond the Anatomy of Renal Nerves: Functional Diversity of Renal Nerves.Journal of cardiovascular translational research · 2022
    Article
  5. Review
  6. Renal denervation in hypertension patients: Proceedings from an expert consensus roundtable cosponsored by SCAI and NKF.Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions · 2021
    Article
  7. Article
  8. Review
  9. Review
  10. Cardiovascular therapeutics · 2020
    Review
  11. Mechanisms underlying the effects of renal denervation in renovascular hypertension.Hypertension research : official journal of the Japanese Society of Hypertension · 2019
    Article
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Raymond R TownsendPerelman School of Medicine, Renal, Electrolyte and Hypertension Division, University of Pennsylvania, 122 Founders Building, 3400 Spruce Street, Philadelphia, PA, 19104, USA. townsend@upenn.edu.
Paul A SobotkaThe Ohio State, Columbus, OH, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purpose of reviewThis review was undertaken to update readers on the field of therapeutic renal denervation for hypertension during the 2016 through 2018 period. RECENT

findingsAfter the failure of Symplicity HTN-3 to meet its top line objective, intense scrutiny revealed several possible concerns addressed by the newer investigations into the area of renal denervation. These included better device technology, more intense subject monitoring for off-protocol antihypertensive drug usage, and deeper penetration into the renal vasculature by the interventionist. Whether untreated by medication for hypertension or on antihypertensive medication, renal denervation shows a clear, though moderate, blood pressure reduction. The failure of roughly one out of three patients with hypertension to respond to denervation procedures argues that there is room for improvement in choosing the optimal patient for this approach to hypertension management.

Indexed as

Radiofrequency AblationClinical Trials as TopicHumansHypertensionKidneySympathectomySympathetic Nervous SystemAlcohol ablationHypertensionRadiofrequency ablationRenal denervationUltrasound ablation

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.