Evidence map›Paper›PMID 30203117›Full record

ArticleAnnals of intensive care2018

Effects of positive end-expiratory pressure strategy in supine and prone position on lung and chest wall mechanics in acute respiratory distress syndrome.

Mehdi Mezidi, Francisco José Parrilla, Hodane Yonis, Zakaria Riad, Stephan H Böhm, Andreas D Waldmann, Jean-Christophe Richard, Floriane Lissonde, Romain Tapponnier, Loredana Baboi and 2 more

Registry-linked trialOpen access · goldAbstract read
In one paragraph

Article in Annals of intensive care, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02416037 (Trans-Pulmonary Pressure and Prone Position in Ards Patients), which is not on this map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02416037 nacompletednot on this map

Trans-Pulmonary Pressure and Prone Position in Ards Patients

TypeinterventionalSponsorHospices Civils de LyonRan2016 to 2017Enrolled32ConditionsAcute Respiratory Distress SyndromeArmslevel of positive end expiratory pressure (Prone Proseva), level of positive end expiratory pressure (Prone Talmor)
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 36 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Review
  7. Article
  8. Review
  9. Article
  10. Esophageal Manometry.Respiratory care · 2020
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 4 countries.

Mehdi MezidiService de Réanimation Médicale, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France.
Francisco José ParrillaIntensive Care Unit, Sant Pau Hospital, Barcelona, Spain.
Hodane YonisService de Réanimation Médicale, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France.
Zakaria RiadService de Réanimation Médicale, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France.
Stephan H BöhmDepartment of Anesthesiology and Intensive Care Medicine, Rostock University Medical Center, Schillingallee 35, 18057, Rostock, Germany.
Andreas D WaldmannSwisstom AG, Lanquart, Switzerland.
Jean-Christophe RichardService de Réanimation Médicale, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France.
Floriane LissondeService de Réanimation Médicale, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France.
Romain TapponnierService de Réanimation Médicale, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France.
Loredana BaboiService de Réanimation Médicale, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France.
Jordi ManceboIntensive Care Unit, Sant Pau Hospital, Barcelona, Spain.
Claude GuérinService de Réanimation Médicale, Hôpital de la Croix-Rousse, Hospices Civils de Lyon, Lyon, France. claude.guerin@chu-lyon.fr.
Hôpital de la Croix-Rousse · FRUniversité Claude Bernard Lyon 1 · FRHospital de Sant Pau · ESKliniken der Stadt Köln · DEUniversity of Rostock · DE

Funding

ESICM Bernhardt Draeger
6 · The paper itself

Abstract

backgroundIn acute respiratory distress syndrome (ARDS) patients, it has recently been proposed to set positive end-expiratory pressure (PEEP) by targeting end-expiratory transpulmonary pressure. This approach, which relies on the measurement of absolute esophageal pressure (Pes), has been used in supine position (SP) and has not been investigated in prone position (PP). Our purposes were to assess Pes-guided strategy to set PEEP in SP and in PP as compared with a PEEP/FIO

resultsWe performed a prospective, physiologic study in two ICUs in university hospitals on ARDS patients with PaO

conclusionsThere was no impact of PP on Pes measurements. PP had an immediate improvement effect on lung mechanics and a late lung recruitment effect independent of PEEP strategy.

Indexed as

Acute respiratory distress syndromeElectrical impedance tomographyEsophageal pressurePositive end-expiratory pressureProne positionTranspulmonary pressure

Identifiers

PMID30203117
PMCPMC6134472
OpenAlexW2891394901

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.