Evidence map›Paper›PMID 30203098›Full record

ArticleJournal of animal science2018

Fermented corn-soybean meal elevated IGF1 levels in grower-finisher pigs.

Lujie Fan, Mingle Dou, Xiaoyu Wang, Qichun Han, Bo Zhao, Jianhong Hu, Gongshe Yang, Xin'e Shi, Xiao Li

Open access · bronzeAbstract readClinical Trial, Veterinary
In one paragraph

Article in Journal of animal science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 36% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. A Poly(dA:dT) Tract in theAnimals : an open access journal from MDPI · 2022
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Lujie FanCollege of Animal Science and Technology, Northwest A & F University, Yangling, Shaanxi, P. R. China.
Mingle DouCollege of Animal Science and Technology, Northwest A & F University, Yangling, Shaanxi, P. R. China.
Xiaoyu WangCollege of Animal Science and Technology, Northwest A & F University, Yangling, Shaanxi, P. R. China.
Qichun HanCollege of Animal Science and Technology, Northwest A & F University, Yangling, Shaanxi, P. R. China.
Bo ZhaoTongchuan Yuanheng Ecological Agriculture Co., Ltd., Tongchuan, Shaanxi, P. R. China.
Jianhong HuCollege of Animal Science and Technology, Northwest A & F University, Yangling, Shaanxi, P. R. China.
Gongshe YangCollege of Animal Science and Technology, Northwest A & F University, Yangling, Shaanxi, P. R. China.
Xin'e ShiCollege of Animal Science and Technology, Northwest A & F University, Yangling, Shaanxi, P. R. China.
Xiao LiCollege of Animal Science and Technology, Northwest A & F University, Yangling, Shaanxi, P. R. China.
Northwest A&F University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Fermentation has attracted increasing attention in pig industry, because of low costs and numerous benefits on pig growth and health as well as environmental improvement, although the mechanisms remain largely unknown. In the present study, fermented corn-soybean meal significantly improved average daily gain and gain:food ratio (P < 0.05). Fermented feed (FF) significantly increased insulin-like growth factor 1 (IGF1) transcription in liver (P < 0.05). Meanwhile, fermented meal significantly enhanced the binding of CCAAT/enhancer-binding protein beta (C/EBPβ) to IGF1 promoter and C/EBPβ expression in liver (both P < 0.05). FF tended to increase IGF1 proteins in liver and serum too (both 0.05 < P < 0.10). Meanwhile, FF slightly but significantly increased hepatic and circulating triglyceride and total cholesterol levels, as well as serum ratio of high-density to low-density cholesterol (all P < 0.05). Our data indicated that FF could significantly augment the binding of C/EBPβ to IGF1 promoter and promote hepatic IGF1 expression and production, thus boost pig growth.

Indexed as

Glycine maxZea maysAnimal FeedAnimal Nutritional Physiological PhenomenaAnimalsBioreactorsFermentationGene Expression RegulationInsulin-Like Growth Factor ILiverMaleSwineTriglyceridesInsulin-Like Growth Factor ITriglycerides

Identifiers

PMID30203098
PMCPMC6276558
OpenAlexW2890980049

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.