ArticleSocial cognitive and affective neuroscience2018
Oxytocin reduces neural activation in response to infant faces in nulliparous young women.
Article in Social cognitive and affective neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.
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Who cites it
12 citing papers in PubMed, 1 synthesis or guideline pooled it, 48 citations in OpenAlex.
- The effect of intranasal oxytocin on social reward processing in humans: a systematic review.Frontiers in psychiatry · 2023Pooled it
- Preliminary data on oxytocin modulation of neural reactivity in women to emotional stimuli of children depending on childhood emotional neglect.Developmental psychobiology · 2023Trial
- Birthing parents' neural response to infant cry: moderating effects of oxytocin and perceived childhood care.Social cognitive and affective neuroscience · 2025Article
- The scent of cuteness-neural signatures of infant body odors.Social cognitive and affective neuroscience · 2024Article
- Article
- Attachment Reminders Trigger Widespread Synchrony across Multiple Brains.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- Creation and Validation of the Japanese Cute Infant Face (JCIF) Dataset.Frontiers in psychology · 2022Article
- The Influence of Infant Schema Cues on Donation Intention in Charity Promotion.Frontiers in psychology · 2022Article
- Mother brain is wired for social moments.eLife · 2021Article
- The Role of Intranasal Oxytocin on Social Cognition: An Integrative Human Lifespan Approach.Current behavioral neuroscience reports · 2020Article
- Article
- Effects of Viewing Cute Pictures on Quiet Eye Duration and Fine Motor Task Performance.Frontiers in psychology · 2020Article
Corrections and comments
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Infant faces have distinctive features that together are described as baby schema, a configuration that facilitates caregiving motivation and behavior, and increases the perception of cuteness. In the current functional magnetic resonance imaging (fMRI) study, we investigated the effect of a within-subjects intranasal oxytocin administration (24 IU) and caregiving motivation on neural responses to infant faces of varying baby schema in 23 healthy nulliparous women. Overall, infant faces elicited activation in several brain regions involved in reward and salience processing, including the ventral tegmental area (VTA), putamen, amygdala, anterior cingulate cortex (ACC), and insula, and this activation was related to self-reported caregiving motivation. Critically, whereas we hypothesized enhanced neural caregiving-related responses after oxytocin administration, we observed reduced activation in the VTA, putamen and amygdala after oxytocin compared to placebo. In nulliparous women, oxytocin has been shown to reduce neural responses in the same regions in response to social stimuli using other paradigms. Oxytocin might affect neural activation toward social stimuli depending on elicited arousal and personal characteristics. The current study is the first to demonstrate this effect in response to infant faces and thereby adds to specify the role of oxytocin in human social information processing.
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