ArticleSocial cognitive and affective neuroscience2018
Association of the oxytocin receptor gene with attitudinal trust: role of amygdala volume.
Article in Social cognitive and affective neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
8 citing papers in PubMed, 23 citations in OpenAlex.
- Association between arginine vasopressin receptor 1A (Proceedings. Biological sciences · 2023Article
- The neuroanatomy of social trust predicts depression vulnerability.Scientific reports · 2022Article
- Is oxytocin a trust hormone? Salivary oxytocin is associated with caution but not with general trust.PloS one · 2022Article
- Association Between Polymorphism (5-HTTLPR) of the Serotonin Transporter Gene and Behavioral Response to Unfair Distribution.Frontiers in behavioral neuroscience · 2022Article
- Salivary Oxytocin Is Negatively Associated With Religious Faith in Japanese Non-Abrahamic People.Frontiers in psychology · 2021Article
- Neurobiological Bases of Social Networks.Frontiers in psychology · 2021Review
- TheDiabetes, metabolic syndrome and obesity : targets and therapy · 2019Article
- Association of Polymorphism of Arginine-Vasopressin Receptor 1A (Frontiers in human neuroscience · 2019Article
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Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous studies have shown that genetic variations in rs53576, a common variant of the oxytocin receptor gene (OXTR) resulting from a single nucleotide polymorphism involving an adenine (A)/guanine (G) transition, are associated with attitudinal trust in men. However, the pathway from gene to behaviour has not been elucidated. We conducted the present study to determine whether amygdala volume mediates the association between OXTR rs53576 genotypes and attitudinal trust. Our results revealed that the left amygdala volume was significantly smaller in GG men than in AA and AG men, whereas it was significantly smaller in AA and AG women than in GG women. In addition, the left amygdala volume was negatively associated with attitudinal trust in men, whereas there was no such association in women. We also found a significant mediation effect of the left amygdala volume on the association between OXTR rs53576 genotypes and attitudinal trust in men. The results of our study suggest that the left amygdala volume plays a pivotal role in the association between OXTR rs53576 genotypes and attitudinal trust in men.
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