ArticleJournal of the Endocrine Society2018
High Prevalence of Radiological Vertebral Fractures in Patients With TSH-Secreting Pituitary Adenoma.
Article in Journal of the Endocrine Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 30 citations in OpenAlex.
- Osteometabolic complications in patients with secreting pituitary adenomas: Is there an impact of gender?Pituitary · 2026Review
- Bone microarchitecture assessed by HR-pQCT in syndrome of inappropriate secretion of thyrotropin with thyrotoxicosis.Archives of osteoporosis · 2026Article
- Long-term effect on bone mineral density of denosumab in the treatment of hyperpituitarism driven osteoporosis: an exploratory study.Pituitary · 2026Article
- TSH-secreting pituitary adenomas and bone.Pituitary · 2024Article
- New insights into the vitamin D/PTH axis in endocrine-driven metabolic bone diseases.Endocrine · 2024Review
- Article
- Vertebral fractures in patients with non-functioning pituitary adenomas - a new frontier?Pituitary · 2024Article
- Acromegaly and Bone: An Update.Endocrinology and metabolism (Seoul, Korea) · 2023Review
- An Aggressive Plurihormonal Pituitary Adenoma With Thyrotropin, Growth Hormone, and Prolactin Excess.JCEM case reports · 2023Article
- High prevalence of vertebral fractures associated with preoperative cortisol levels in patients with recent diagnosis of Cushing disease.Annals of medicine · 2023Article
- Clinical Biology of the Pituitary Adenoma.Endocrine reviews · 2022Review
- COVID-19 and the pituitary.Pituitary · 2021Review
- Hypovitaminosis D and the endocrine phenotype of COVID-19.Endocrine · 2021Review
- Radiological Thoracic Vertebral Fractures are Highly Prevalent in COVID-19 and Predict Disease Outcomes.The Journal of clinical endocrinology and metabolism · 2021Article
- Hyperprolactinemia and bone.Pituitary · 2020Review
- Risk of vertebral fractures in hypoparathyroidism.Reviews in endocrine & metabolic disorders · 2019Review
- Use of antiosteoporotic drugs and calcium/vitamin D in patients with fragility fractures: impact on re-fracture and mortality risk.Endocrine · 2019Observational
Corrections and comments
- Erratum issued
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundBone loss and high risk of fractures have been reported in patients with primary hyperthyroidism, whereas data on skeletal health in TSH-secreting adenoma (TSH-oma) are scant, and the risk of fractures in this specific clinical context has not been investigated so far. In this cross-sectional study, we aimed at evaluating for the first time, to our knowledge, the prevalence and determinants of radiological vertebral fractures (VFs) in patients with TSH-oma.
methodsTwenty-two patients (10 males, 12 females; median age 47 years) with TSH-oma and 44 patients (20 males, 24 females; median age 49 years) with nonfunctioning pituitary adenoma (NFPA) were retrospectively evaluated for thoracic VFs using a morphometric approach on lateral chest X-ray routinely performed in the presurgical diagnostic workup.
resultsThe prevalence of VFs was significantly higher in TSH-oma vs NFPA (59.1% vs 22.7%;
conclusionsThis study provides the first evidence, to our knowledge, that patients with TSH-oma may develop VFs in close relationship with severity of hyperthyroidism.
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