ArticleScience advances2018
Progressive fuzzy cation-π assembly of biological catecholamines.
Article in Science advances, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed.
- Underwater self-curing and adhesion of phenolic polymer coacervate with negligible external stimuli.Materials today. Bio · 2026Article
- Beyond Molecular Determinism: State-Convergent Polymerization as a Functional Design Principle Under Chemical Complexity.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Ultrasmooth and thin pheomelanin-like film as a metal-free electrocatalytic enhancer.Chemical science · 2026Article
- Melanin-like Materials for Photothermal Applications: Recent Advancements and Future Directions.Molecules (Basel, Switzerland) · 2026Review
- Application of melanin and its engineered nanomaterials in tumor radiotherapy: a review.Journal of translational medicine · 2026Review
- Linker-Engineered Tyrosine-Azide Coatings for Stable Strain-Promoted Azide-Alkyne Cycloaddition (SPAAC) Functionalization.Polymers · 2025Article
- Mussel-Inspired Self-Assembly of PtOAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- Molecular engineering of melanin for enhanced biological γ-ray protection.Nature communications · 2025Article
- Extracellular Matrix-Mediated Crosslinking of Adhesive Hyaluronic Acid Patch for Treating Volumetric Muscle Injury.Advanced healthcare materials · 2025Article
- Regulation of melanin production in fungi.Frontiers in fungal biology · 2025Review
- Comediation of voltage gating and ion charge in MXene membrane for controllable and selective monovalent cation separation.Science advances · 2024Article
- Effect of Polydopamine Nanoparticle-Induced Surface Modification on Demineralized Dentin for Enhanced Functional Remineralization.Journal of pharmacy & bioallied sciences · 2024Article
- Pressure enabled organic reactions via confinement between layers of 2D materials.Science advances · 2024Article
- Cu-ZnO Embedded in a Polydopamine Shell for the Generation of Antibacterial Surgical Face Masks.Molecules (Basel, Switzerland) · 2024Article
- MimickingInnovation (Cambridge (Mass.)) · 2024Article
- Cationic Curcumin Nanocrystals Liposomes for Improved Oral Bioavailability: Formulation Development, Optimization, In Vitro and In Vivo Evaluation.Pharmaceutics · 2024Article
- Photonic control of ligand nanospacing in self-assembly regulates stem cell fate.Bioactive materials · 2024Article
- Pyrrole-Doped Polydopamine-Pyrrole (PDA-nPY) Nanoparticles with Tunable Size and Improved NIR Absorption for Photothermal Therapy.Pharmaceuticals (Basel, Switzerland) · 2023Article
- Expanding the Scope of an Amphoteric Condensed Tannin, Tanfloc, for Antibacterial Coatings.Journal of functional biomaterials · 2023Article
- Site-specific fabrication of a melanin-like pigment through spatially confined progressive assembly on an initiator-loaded template.Nature communications · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Biological functions depend on biomolecular assembly processes. Assemblies of lipid bilayers, actins, microtubules, or chromosomes are indispensable for cellular functions. These hierarchical assembly processes are reasonably predictable by understanding chemical structures of the defined building blocks and their interactions. However, biopigment assembly is rather fuzzy and unpredictable because a series of covalently coupled intermediates from catecholamine oxidation pathways progressively form a higher-level hierarchy. This study reports a different yet unexplored type of assembly process named "cation-π progressive assembly." We demonstrated for the first time that the cation-π is the primary mechanism for intermolecular assembly in dopamine-melanin biopigment. We also found that the self-assembled products physically grow and chemically gain new functions "progressively" over time in which cation-π plays important roles. The progressive assembly explains how biological systems produce wide spectra of pigment colors and broad wavelength absorption through energy-efficient processes. Furthermore, we also demonstrate surface-independent wettability control using cation-π progressive assembly.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.