Evidence map›Paper›PMID 30202741›Full record

ArticleClinical and experimental reproductive medicine2018

Associations of serum fetuin-A and oxidative stress parameters with polycystic ovary syndrome.

Sibel Sak, Hacer Uyanikoglu, Adnan Incebiyik, Hatice Incebiyik, Nese Gul Hilali, Tevfik Sabuncu, Erdal Sak

Open access · diamondAbstract read
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Article in Clinical and experimental reproductive medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it, 31 citations in OpenAlex.

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  16. Polycystic ovary syndrome and mitochondrial dysfunction.Reproductive biology and endocrinology : RB&E · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Sibel SakDepartment of Obstetrics and Gynaecology, Faculty of Medicine, Harran University, Sanliurfa, Turkey.
Hacer UyanikogluDepartment of Obstetrics and Gynaecology, Faculty of Medicine, Harran University, Sanliurfa, Turkey.
Adnan IncebiyikDepartment of Obstetrics and Gynaecology, Faculty of Medicine, Harran University, Sanliurfa, Turkey.
Hatice IncebiyikDepartment of Endocrinology, Faculty of Medicine, Harran University, Sanliurfa, Turkey.
Nese Gul HilaliDepartment of Obstetrics and Gynaecology, Faculty of Medicine, Harran University, Sanliurfa, Turkey.
Tevfik SabuncuDepartment of Endocrinology, Faculty of Medicine, Harran University, Sanliurfa, Turkey.
Erdal SakDepartment of Obstetrics and Gynaecology, Faculty of Medicine, Harran University, Sanliurfa, Turkey.
Harran University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study was to compare serum fetuin-A levels and oxidative stress markers, as indicators of insulin resistance, in women with polycystic ovary syndrome (PCOS) and in healthy controls.

methodsThis prospective case-control study included 46 patients with PCOS and 48 age- and body mass index-matched control women. Levels of serum hormones, fetuin-A, and oxidative stress markers were measured in blood samples taken during the early follicular period from each participant.

resultsFollicle-stimulating hormone (FSH), luteinising hormone (LH), total testosterone levels, and the LH/FSH ratio were found to be significantly higher in women with PCOS than in controls. Serum total antioxidant status, total oxidant status, and oxidative stress index parameters all indicated significantly higher levels of oxidative stress in PCOS patients than in controls. Serum fetuin-A levels, which were analyzed as an indicator of insulin resistance, were higher in the PCOS group than in the control group (210.26±65.06 µg/mL and 182.68±51.20 µg/mL, respectively;

conclusionThe data obtained from the present study suggest that higher levels of both serum fetuin-A and oxidative stress markers might be related with PCOS.

Indexed as

Fetuin-AOxidative stressPolycystic ovary syndrome

Identifiers

PMID30202741
PMCPMC6125147
OpenAlexW2890376048

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.