Evidence map›Paper›PMID 30202614›Full record

ArticleTurkish journal of ophthalmology2018

A Custom-made Pupillometer System for Characterizing Pupillary Light Response.

Nefati Kıylıoğlu, Mahmut Alp Kılıç, Tolga Kocatürk, Seyhan Bahar Özkan, Mehmet Bilgen

Open access · diamondAbstract read
In one paragraph

Article in Turkish journal of ophthalmology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Nefati KıylıoğluAdnan Menderes University Faculty of Medicine, Department of Neurology, Division of Clinical Neurophysiology, Aydın, Turkey.ORCID https://orcid.org/0000-0001-5783-1719
Mahmut Alp KılıçAdnan Menderes University Faculty of Medicine, Department of Neurology, Division of Clinical Neurophysiology, Aydın, Turkey.ORCID https://orcid.org/0000-0003-2645-1988
Tolga KocatürkAdnan Menderes University Faculty of Medicine, Department of Ophthalmology, Aydın, Turkey.ORCID https://orcid.org/0000-0001-5187-227X
Seyhan Bahar ÖzkanAdnan Menderes University Faculty of Medicine, Department of Ophthalmology, Aydın, Turkey.ORCID https://orcid.org/0000-0002-0469-4885
Mehmet BilgenAdnan Menderes University Faculty of Medicine, Department of Biophysics, Aydın, Turkey.ORCID https://orcid.org/0000-0001-5671-2021
Adnan Menderes University · TR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis paper presents the design and construction of a viable pupillometer system and demonstrates its merits with extensive validation tests. MATERIALS AND

methodsA web camera was modified by removing its infrared filter and mounted on a chin rest. Light emitting diodes (LEDs) operating at infrared and visible spectra were integrated to provide background and light stimulus, respectively. The LEDs were controlled by a microprocessor board. Stimulation was presented using a periodic paradigm with variable period and duty cycle. Videos of both pupils were recorded at 30 frames/second and processed offline using software developed in-house. The overall system was validated with data gathered from individuals with healthy vision under different stimulation paradigms. Temporal variations in pupil size were determined and analyzed statistically.

resultsThe analysis revealed that the pupil sizes were accurately measured from the video frames provided that reflections from both infrared and visible lights remain outside the pupil. The system achieved moderate to excellent repeatability scores (87.8 and 86.8% for short 1 second and long 2 second pulses, respectively), which demonstrated its effectiveness and confirmed that it can be used reliably as a pupillometer.

conclusionThe proposed pupillometer system produces useful, quantitative data characterizing pupillary light response. However, further development and implementation are needed to potentially turn it into a low-cost alternative for other studies involving the autonomic nervous system, cognitive function, drug metabolism, pain response, psychology, fatigue, and sleep disorders.

Indexed as

Pupillary light reflexpupillary responsepupillometer

Identifiers

PMID30202614
PMCPMC6126101
OpenAlexW2890976612

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.