Evidence map›Paper›PMID 30202599›Full record

ReviewBJPsych open2018

Psychological interventions for bipolar disorder in low- and middle-income countries: systematic review.

Mekdes Demissie, Charlotte Hanlon, Rahel Birhane, Lauren Ng, Girmay Medhin, Abebaw Fekadu

Registry-linked trialAbstract readReview
In one paragraph

Review in BJPsych open, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04671225 (Psychoeducation for Patients With Bipolar Disorder in Rwanda), which is not on this map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04671225 nacompletednot on this mapstarted 2021, after this paper: background citation

Psychoeducation for Patients With Bipolar Disorder in Rwanda

TypeinterventionalSponsorUniversity of AarhusRan2021 to 2022Enrolled154ConditionsBipolar DisorderArmsGroups Psychoeducation, Waiting-list
3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Mekdes DemissieLecturer, College of Health Sciences, Department of Psychiatry, Addis Ababa University, Ethiopia.
Charlotte HanlonAssociate Professor, College of Health Sciences, Department of Psychiatry, Addis Ababa University, Ethiopia and Centre for Global Mental Health, Institute of Psychiatry, Psychology and Neuroscience, Health Services and Population Research, King's College London, UK.
Rahel BirhaneResearch Assistant, College of Health Sciences, Department of Psychiatry, Addis Ababa University, Ethiopia.
Lauren NgAssistant Professor, School of Medicine, Boston University, USA.
Girmay MedhinAssociate Professor, Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Ethiopia.
Abebaw FekaduAssociate Professor, College of Health Sciences, Department of Psychiatry and Centre for Innovative Drug Development and Therapeutic Studies for Africa (CDT-Africa), Collage of Health Science, Addis Ababa University, Ethiopia and Department of Global Health and Infection, Brighton and Sussex Medical School, University of Sussex and Center for Affective Disorders, Institute of Psychiatry, Psychology and Neuroscience, Department of Psychological Medicine, King's College London, UK.

Funding

Posttraumatic Stress Disorder Intervention for People with Severe Mental Illness in Low- and Middle-Income Country Primary Care SettingsK23MH110601 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI NG, LAUREN CHRISTINA · 2016 to 2021
$1.0M
Medical Research Council MR/M025470/1NIMH NIH HHS K23 MH110601
6 · The paper itself

Abstract

backgroundAdjunctive psychological interventions for bipolar disorder have demonstrated better efficacy in preventing or delaying relapse and improving outcomes compared with pharmacotherapy alone.

aimsTo evaluate the efficacy of psychological interventions for bipolar disorder in low- and middle-income countries.

methodA systematic review was conducted using PubMed, PsycINFO, Medline, EMBASE, Cochrane database for systematic review, Cochrane central register of controlled trials, Latin America and Caribbean Center on Health Science Literature and African Journals Online databases with no restriction of language or year of publication. Methodological heterogeneity of studies precluded meta-analysis.

resultsA total of 18 adjunctive studies were identified: psychoeducation (

conclusionsAdjunctive psychological interventions alongside pharmacotherapy appear to improve the clinical outcome and quality of life of people with bipolar disorder in middle-income countries. Further studies are required to investigate contextual adaptation and the role of non-specialists in the provision of psychological interventions to ensure scalability and the efficacy of these interventions in low-income country settings. DECLARATION OF INTEREST: None.

Indexed as

bipolar affective disorderslow- and middle-income countriesPsychosocial interventions

Identifiers

PMID30202599
PMCPMC6127962

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.