Evidence map›Paper›PMID 30202512›Full record

ArticleJournal of tissue engineering

Biomimetic oyster shell-replicated topography alters the behaviour of human skeletal stem cells.

Shona J Waddell, María C de Andrés, Penelope M Tsimbouri, Enateri V Alakpa, Maggie Cusack, Matthew J Dalby, Richard Oc Oreffo

Open access · goldAbstract read
In one paragraph

Article in Journal of tissue engineering. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.6field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 23 citations in OpenAlex.

  1. Article
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  10. From the raw bar to the bench: Bivalves as models for human health.Developmental and comparative immunology · 2019
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Shona J WaddellCentre for Human Development, Stem Cells and Regeneration, Institute of Developmental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
María C de AndrésCentre for Human Development, Stem Cells and Regeneration, Institute of Developmental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
Penelope M TsimbouriCentre for Cell Engineering, Institute of Molecular, Cell and Systems Biology, CMVLS, University of Glasgow, Glasgow, UK.
Enateri V AlakpaDepartment of Integrative Medical Biology, Umeå University, Umeå, Sweden.
Maggie CusackDivision of Biological and Environmental Science, University of Stirling, Stirling, UK.
Matthew J DalbyCentre for Cell Engineering, Institute of Molecular, Cell and Systems Biology, CMVLS, University of Glasgow, Glasgow, UK.
Richard Oc OreffoCentre for Human Development, Stem Cells and Regeneration, Institute of Developmental Sciences, Faculty of Medicine, University of Southampton, Southampton, UK.
University of Southampton · GBUniversity of Glasgow · GBUmeå University · SEUniversity of Stirling · GB

Funding

Biotechnology and Biological Sciences Research Council BB/G008868/1Biotechnology and Biological Sciences Research Council JF20604Chief Scientist Office CZB/4/714Medical Research Council MR/K011278/1Medical Research Council MR/K026682/1
6 · The paper itself

Abstract

The regenerative potential of skeletal stem cells provides an attractive prospect to generate bone tissue needed for musculoskeletal reparation. A central issue remains efficacious, controlled cell differentiation strategies to aid progression of cell therapies to the clinic. The nacre surface from

Indexed as

bone regenerationNacreosteogenic differentiationskeletal stem celltopography

Identifiers

PMID30202512
PMCPMC6124183
OpenAlexW2891152207

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.